Results 121 to 130 of about 12,027,799 (306)

Cause-specific mortality rates.

, 2018
The figure shows the total number of deaths by FTIMR group for the years 2010–2012 as well as the percentage of deaths in each group in the different cause-of-death categories. The following ICD-10 causes of death were included: congenital malformations,
Neha Bairoliya (4984337), Günther Fink (299519)   +1 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Educational differences in all-cause mortality by marital status [PDF]

Using life table measures, we compare educational differentials in all-cause mortality at ages 40 to 70 in Bulgaria to those in Finland and the United States. Specifically, we assess whether the relationship between education and mortality is modified by
Pekka Martikainen, Irma Elo, Iliana V. Kohler, Kirsten P. Smith   +3 more
core  

Cause-specific mortality rates in patients with diabetes according to comorbid macro- and microvascular complications: BioBank Japan Cohort [PDF]

Patients with diabetic nephropathy have the highest mortality rates of all causes, cancer, and macrovascular and infectious diseases. The primary cause of death of patients with diabetes with and without all vascular complications was cancer.
Nagai, Akiko, 25509, 40422688, 横道, 洋司, Hirata, Makoto, 10210337, Yokomichi, Hiroshi, 25512, Yamagata, Zentaro, 望月, 美恵, 24118, BioBank Japan Project, コジマ, レイジ, 山縣, 然太朗, Mochizuki, Mie, 24294, 20596879, 10523780, モチヅキ, ミエ, 小島, 令嗣, Kojima, Reiji, ヤマガタ, ゼンタロウ, ヨコミチ, ヒロシ   +22 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Cause-specific mortality per 1,000 population among mothers (10-year cumulative incidence risk), April 1, 2002, to December 31, 2014.

, 2019
Cause-specific mortality per 1,000 population among mothers (10-year cumulative incidence risk), April 1, 2002, to December 31, 2014.
Ruth Gilbert (122786), Linda Wijlaars (6377441), Maria Chiu (3438533), Abby Amartey (8044076), Katie Harron (312648), Limei Zhou (810652), Natasha Saunders (4320754), Ruth Blackburn (496926), Astrid Guttmann (242362)   +8 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Appendix G. Additional cause-specific mortality results.

, 2016
Additional cause-specific mortality ...
Peter J. Mahoney (2927121), John F. Benson (2615461), Brent R. Patterson (2615458)   +2 more
core   +1 more source

Association between dietary flavonol intake and mortality risk in the U.S. adults from NHANES database

Scientific Reports
Using updated National Health and Nutrition Examination Survey (NHANES) follow-up data, and a large nationwide representative sample of adult U.S. citizens, the aim of this study was to explore the relationship between dietary flavonol intake, all-cause ...
Zhiqiang Zong, Xiang Cheng, Yang Yang, Jianchao Qiao, Jiqing Hao, Fanfan Li   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source