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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
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Design of (<i>R</i>)-3-(5-Thienyl)carboxamido-2-aminopropanoic Acid Derivatives as Novel NMDA Receptor Glycine Site Agonists: Variation in Molecular Geometry to Improve Potency and Augment GluN2 Subunit-Specific Activity. [PDF]
J Med ChemZhao F +18 more
europepmc +1 more source
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Variability of specific activities and specific-activity ratios
Archives of Biochemistry and Biophysics, 1957Abstract In studies involving the use of specific activities or specific-activity ratios, the amount of the P32 inoculum will apparently have no effect on the coefficient of variation of the results. Dilution of the biological material prior to fractionation, dilution of the digested fractions, or loss of material during digestion will lead to a rise
R L, STEARMAN, T G, WARD
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Active Specific and Active Non-Specific Immunotherapy in Patients with Malignant Melanoma
Oncology, 2009Patients in clinical stage I–III of malignant melanoma were treated after resection of the tumor mass with membrane extracts of autologous tumor tissue and BCG or BCG alone. They were monitored immunologically by delayed cutaneous hypersensitivity reactions, i.e.
E M, Kokoschka, C, Cerni, M, Micksche
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A brain-specific transcription activator
Neuron, 1989We have identified a DNA binding protein, named BETA, that interacts with the same (B) transcriptional regulatory sequence as the known transcription factor NF-kappa B. BETA is found only in gray matter throughout the brain, and not in a variety of other rat tissues.
M, Korner +4 more
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Specific determination of arylsulfatase A activity
Experientia, 1986Arylsulfatase activities in biological materials are too low to be detected by the methods available hitherto. A sensitive and specific assay method for arylsulfatase A (AS-A) has been developed in the present study. Ascorbate-2-sulfate is known to be a specific natural substrate of AS-A; the ascorbic acid liberated by the action of AS-A was ...
H, Inoue, Y, Seyama, S, Yamashita
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Journal of Pharmaceutical Sciences, 1966
Trypsin has been fractionated electrophoret ically on cellulose acet ate into four tones. The lead zone, which contains the tryptic activity, was treated with specific substrate for enzyme activity and with the Lowry test for protein content. Specific activity of pure trypsin appears to be slightly greater than 8000 N.F. u./mg.
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Trypsin has been fractionated electrophoret ically on cellulose acet ate into four tones. The lead zone, which contains the tryptic activity, was treated with specific substrate for enzyme activity and with the Lowry test for protein content. Specific activity of pure trypsin appears to be slightly greater than 8000 N.F. u./mg.
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Activation and validation of the system specifications
Microprocessing and Microprogramming, 1991Presentation of the potential behavior of the future software system after earliest phases of the software development process is a key problem annotated in this paper. How to do this presentation to a customer team after the requirements analysis or between them?
József Györkös +2 more
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