Results 51 to 60 of about 62,450 (242)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Engineered NiCo-LDH nanosheets- and ZnFe2O4 nanocubes-decorated carbon nanofiber bonded mats for high-rate asymmetric supercapacitors

Green Energy & Environment, 2022
In this work, we have prepared the hierarchically nanostructured core–shell NiCo layered double hydroxide (NiCo-LDH) nanosheets- and ZnFe2O4 nanocubes-decorated polyacrylonitrile (PAN)/pitch-based carbon nanofibers (PPCNs) webs (NiCo-LDH@PPCNs as cathode
Jae-Gyoung Seong, Tae Hoon Ko, Danyun Lei, Woong-Ki Choi, Yun-Su Kuk, Min-Kang Seo, Byoung-Suhk Kim   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Synthesis of Porous Carbon by Activation Method and its Electrochemical Performance

International Journal of Electrochemical Science, 2018
For potential applications in supercapacitors, Porous carbon has been synthesized by the facile and economic activation method. The SEM and XRD are adopted to analyze the microstructure and the specific surface area.
Wang Kai, Zhou Shengzhe, Zhou Yanting, Ren Jun, Li Liwei, Lan Yong   +5 more
doaj   +1 more source

Synergetic Effect of RuO2 Nanosheets as a Redox Active Binder for Aqueous Electrochemical Capacitors: The Case of MnO2

Electrochemistry, 2020
MnO2 has been considered as a promising positive electrode material for aqueous electrochemical capacitors combined with activated carbon negative electrodes.
Ryota SAITO, Yusuke SATO, Daisuke TAKIMOTO, Sho HIDESHIMA, Wataru SUGIMOTO   +4 more
doaj   +1 more source

Allele-specific DNA methylation capacitates PEAR1 enhancer activity

, 2016
sponsorship: This work was supported by the "Fonds voor Wetenschappelijk Onderzoek (FWO) Vlaanderen" grant G0A6514N and by the "Programmafinanciering KU Leuven (PF/10/014)." B.I. and M.P. are both FWO postdoctoral fellows (12M2715N and 1288714N, respectively); P.V. holds a FWO senior clinical investigator grant (1801414N).
Izzi, Benedetta, Pistoni, Elena, Cludts, Katrien, Akkor, Pinar, Lambrechts, Diether, Verfaillie, Catherine, Verhamme, Peter, Freson, Kathleen, Hoylaerts, Marc   +8 more
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Flexible Supercapacitors using Liquid Phase Exfoliated Graphene with Enhanced Specific Capacitance

International Journal of Electrochemical Science, 2016
Graphene was synthesized by liquid phase exfoliation of graphite in DMF (N,N-Dimethylformamide) organic solvent. The synthesized graphene was characterized by TEM, SEM, UV-Visible and Raman spectrum. Graphene based paper electrodes were prepared by brush
Randhir Singh, C.C. Tripathi
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source