Results 71 to 80 of about 13,995,485 (256)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Spatial Development and Energy Consumption [PDF]

open access: yes
Previous literature has suggested that the urban form (i.e., city size, density, and center distribution pattern) influences urban energy consumption.
Harrington, Winston   +2 more
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Understanding domestic energy consumption through interactive visualisation: a field study

open access: yes, 2012
Motivated by the need to better manage energy demand in the home, in this paper we advocate the integration into Ubicomp systems of interactive energy consumption visualisations, that allow users to engage with and understand their consumption data ...
Costanza, Enrico   +8 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Residential Energy Consumption in Urban China [PDF]

open access: yes
Residential energy consumption (REC) is the second largest energy use category (10%) in China and urban residents account for most of the REC. Understanding the underlying drivers of variations of urban REC thus helps to identify challenges and ...
Ma, Chunbo, Li, Na, Zhao, Xiaoli
core  

Power consumption of electric centrifugal pumping plants under extraction of highly watered oil

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов
Relevance. Currently, oil fields in Russia are mainly developed using the method of artificial maintenance of reservoir pressure to achieve high oil recovery.
Roza I. Vakhitova   +2 more
doaj   +1 more source

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