Results 171 to 180 of about 13,252,850 (343)
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Charles Cléophas Person (1801-1884), French physician, transformed into researcher of thermodynamic properties such as latent heats of fusion, vaporization, and dilution, the specific heat of pure compounds and saline solutions, thermometry, neural ...
Jaime Wisniak
doaj
Specific Heat Capacity and Thermal Conductivity Measurements of PLA-Based 3D-Printed Parts with Milled Carbon Fiber Reinforcement. [PDF]
Blanco I, Cicala G, Recca G, Tosto C.
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Entropy of a Quasi-de Sitter Spacetime and the Role of Specific Heat. [PDF]
Luongo O, Azizinia M, Boshkayev K.
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Unifying thermopower: entropy and specific heat in magnetic, superconducting, nanoscale, and frustrated systems. [PDF]
Jazandari M, Abouie J, Vashaee D.
europepmc +1 more source
A 3-D virtual human thermoregulatory model to predict whole-body and organ-specific heat-stress responses. [PDF]
Unnikrishnan G +9 more
europepmc +1 more source

