Results 111 to 120 of about 287,536 (308)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Nganasan Children Literature: History and Specifics

Journal of Siberian Federal University. Humanities & Social Sciences, 2016
В статье представлены результаты исследования нганасанских детских сказок. Раскрыта история происхождения нганасанских детских сказок от мифологических эпических сказаний народа (ситабов) и из исторических национальных преданий (дюрымы). Апробирована возможность приложения морфологического и семантического анализа для понимания нганасанских сказок, в ...
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Post-influenza bacterial infection: mechanisms of pathogenesis and advances in therapeutic strategies

Frontiers in Microbiology
Patients coinfected with influenza virus (IFV) and bacteria face significantly elevated risks of critical illness and mortality. This vulnerability stems primarily from IFV-induced immunosuppression and disruption of respiratory barrier integrity ...
Biao Lei, Shun Wang, Linzhong Yu, Linzhong Yu, Qinhai Ma   +4 more
doaj   +1 more source

The Journal of the Center for Interdisciplinary Teaching and Learning [PDF]

, 2018
IMPACT: The Journal of the Center for Interdisciplinary Teaching & Learning is a peer-reviewed, biannual online journal that publishes scholarly and creative non-fiction essays about the theory, practice and assessment of interdisciplinary education ...
Boger, Kathryn D., Bozzone, Donna, Cook, Susan E., Donohue, Micah, Doyle, Mary Beth, Henley, Liz, Meljac, Eric, Powell, Beth, Sharicz, Carol Ann   +8 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Critical success factors for preventing E-banking fraud [PDF]

, 2013
E-Banking fraud is an issue being experienced globally and is continuing to prove costly to both banks and customers. Frauds in e-banking services occur as a result of various compromises in security ranging from weak authentication systems to ...
Shah, Mahmood
core   +1 more source

Arabic for Specific Purposes in Malaysia: A Literature Review

Issues in Language Studies, 2019
Many universities have introduced Arabic language for specific purpose courses in order to help learners master the terminologies and language patterns used in specific fields. This paper reviews the rising popularity of learning Arabic for specific purposes among Malaysian students in light of a more contemporary needs than decades ago when the Arabic
Mohammad Taufiq Abdul Ghani, Wan Ab Aziz Wan Daud, Saipolbarin Ramli   +2 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source