Results 171 to 180 of about 1,504,335 (301)

Recent Advances in Triboelectric Nanogenerators for Biomedical and Cardiovascular Monitoring. [PDF]

Materials (Basel)
Sarode A, Rajendran J, Slaughter G.
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

A Roadmap for Extreme-Mechanics Hydrogels: From Toughening Mechanisms to Intelligent System Integration. [PDF]

Nanomicro Lett
Tong A, Huang Z, He A, Qiao S, Shi Z, Wang X, Chen Z, Hu P, Wang K, Qian J, Xu W, Chen F.   +11 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Model for evaluating drilling efficiency based on the concept of Mechanical Specific Energy

, 2016
Systems to increase efficiency during drilling is desirable in order to have more costeffective well operations. This master s thesis studies the possibility to present new information real-time regarding the actual drilling efficiency, based on already existing data commonly available during most operations.
Tveit, Øyvind Sæther, Berg, Paal Vegar
openaire   +1 more source

Catalytic High-Speed Reactive Extrusion for Polyethylene Mechanochemical Upcycling. [PDF]

ChemSusChem
Jamalzadeh M, Masembe P, Pujari H, Keller L, Borja MG, Monwar MM, Cui L, Hallac B, Schwendemann D, Sobkowicz MJ.   +9 more
europepmc   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Fabrication and Performance Evaluation of 3D-Printed Zinc-Manganese Flexible Batteries. [PDF]

Materials (Basel)
Ju E, Yan C, Wu L.
europepmc   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Adding a weight to constrain the trunk increases knee joint kinetics during sidestep cutting in female athletes. [PDF]

Sci Rep
Kadlec D, Jordan MJ, Alderson J, Nimphius S.   +3 more
europepmc   +1 more source