Results 61 to 70 of about 103,779 (258)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

EFFECTIVENESS OF FOOTBALL TRAINING ON THE MOTOR ABILITIES OF 12-YEAR OLD STUDENTS

Trakia Journal of Sciences
The issue of developing the motor abilities of students is highly relevant to school-based physical education. Few specialists plan the development of motor qualities in relation to the formation of motor skills, and this is particularly
D. Nancheva, D. Ivanov
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Motor and cognitive growth following a Football Training Program

Frontiers in Psychology, 2015
Football may be a physical and sport activities able to improve motor and cognitive growth in children. Therefore the aim of this study was to assess whether a Football Training Program taken over 6 months would improve motor and cognitive performances ...
Marianna eAlesi, Antonino eBianco, Johnny ePadulo, Giorgio eLuppina, Marco ePetrucci, Antonio ePaoli, Antonio ePalma, Annamaria ePepi   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Development of Motor and Specific Motor Abilities for Athletics in Elementary School Male and Female First-Graders

Collegium antropologicum, 2009
The aim of the study was to determine canonic relations between the set of basic motor variables and the set of athletic variables assessing the abilities of sprint, throw and long-distance run adjusted for children aged seven years. Study sample consisted of 635 first-graders from Split elementary schools, divided into groups of 325 male and 310 ...
Katić, Ratko, Retelj, Edvard, Milat, Sanja, Ivanišević, Snježana, Gudelj, Ines   +4 more
openaire   +4 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

FAKTORSKA STRUKTURA I RELACIJE MOTORIČKIH I SUTUACIONO – MOTORIČKIH SPOSOBNOSTI RUKOMETAŠA [PDF]

Sport Mont, 2005
The motor activity during a handball game is characterized by loads of great intensity and by large scope, which are structured as interval-variable loads.
Saša Marković, Nenad Pivač
doaj  

Relationship between Body Composition and Specific Motor Abilities According to Position in Elite Female Soccer Players. [PDF]

Int J Environ Res Public Health, 2023
Stanković M, Čaprić I, Đorđević D, Đorđević S, Preljević A, Koničanin A, Maljanović D, Nailović H, Muković I, Jelaska I, Sporiš G.   +10 more
europepmc   +1 more source