Results 101 to 110 of about 7,264,357 (271)

Therapeutic Education in Atopic Dermatitis Worldwide: Current Practices and Future Pathways—An Update From the Oriented Patient Education Network of the International Society of Atopic Dermatitis (OpenED‐ISAD)

JEADV Clinical Practice, EarlyView.
ABSTRACT Therapeutic patient education (TPE) is increasingly seen as an essential part of managing atopic dermatitis (AD), helping to connect clinical advice with real‐world adherence. This review aims to summarise current TPE approaches in AD, identify ongoing barriers to adherence, and examine innovations like digital health, shared decision‐making ...
Jean‐François Stalder, Hélène Aubert, Sébastien Barbarot, Pavel Chernyshov, Lawrence F. Eichenfield, Uwe Gieler, Peter Lio, Dagmar Simon, Marketa Saint Aroman, David Troya, Alain Taïeb   +10 more
wiley   +1 more source

Structural and Stability Analysis of de Novo Designed Proteins Incorporating a Plant Self‐Incompatibility Motif

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Artificial protein design enables the creation of stable scaffolds beyond those evolved in nature. Incorporation of native functional motifs into de novo scaffolds provides a promising strategy to mimic natural interactions while altering structural frameworks.
Hakuto Miyoshi, Koya Sakuma, Yoshitaka Moriwaki, Naoki Aoyama, Toma Kashima, Tohru Terada, Akimasa Miyanaga, Shinya Fushinobu   +7 more
wiley   +1 more source

Who Knows, Cares and Acts for Sustainability in Times of Uncertainty? Demographic Differences in Perceived Knowledge, Concerns, and Pro‐Environmental Behaviors

Sustainable Development, EarlyView.
ABSTRACT In 2026, some years after the Covid‐19 pandemic and the related economic crisis, the global landscape remains profoundly unsettled. Geopolitical conflicts, such as the war between Russia and Ukraine and the Middle East conflicts, continue to drive instability, reshaping global priorities and challenges.
Rosa Maria Dangelico, Serena Filippelli, Luca Fraccascia, Andrea Viggiani   +3 more
wiley   +1 more source

Specific phobia in older adults: Evidence from the national epidemiologic survey on alcohol and related conditions

, 2009
OBJECTIVE: This study aims to investigate: 1) the association of specific phobia with childhood parental loss and recent stressful life events; 2) the coexistence of specific phobia and major depressive disorders (MDDs); and 3) the impact of specific ...
Chou, KL
core   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Economic Burden and Treatment Patterns Among Patients Diagnosed With Vitiligo in Japan: An Observational Retrospective Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Vitiligo, a common and chronic depigmentation disorder, significantly impacts patients' quality of life and exerts a substantial economic burden. The deleterious impact of vitiligo can be exacerbated by comorbid conditions, including psychiatric and autoimmune conditions.
Naoki Oiso, Kent A. Hanson, Ahmed M. Soliman, Chao Li, Manabu Taura, Daniel Mercer, Andrew Rava, Danielle Bynoe, Haiyan Sun, Tamio Suzuki   +9 more
wiley   +1 more source

Virtual Reality Exposure Therapy for Treating Fear of Contamination Disorders: A Systematic Review of Healthy and Clinical Populations

Brain Sciences
Virtual Reality Exposure Therapy (VRET), particularly immersive Virtual Reality Exposure Therapy (iVRET), has gained attraction as an innovative approach in exposure therapy (ET), notably for some anxiety disorders with a fear of contamination component,
Francesca Ferraioli, Laura Culicetto, Luca Cecchetti, Alessandra Falzone, Francesco Tomaiuolo, Angelo Quartarone, Carmelo Mario Vicario   +6 more
doaj   +1 more source

Anxiety activating virtual environments for investigating social phobias [PDF]

Social phobia has become one of the commonest manifestations of fear in any society. This fear is often accompanied by major depression or social disabilities.
Kwon, Remi Jounghuem
core  

Nocturnal Behavior of Wintering Common Cranes (Grus grus) Under Varying Environmental Conditions

Integrative Zoology, EarlyView.
For diurnal species, nighttime represents a critical ecological boundary. Understanding the ecological determinants of nocturnal activity in taxa traditionally regarded as inactive after dusk is essential for elucidating the adaptive significance of nighttime behavior. We examined how night phase, nocturnal brightness (moon illumination and cloud cover)
Flavio Monti, Marco Ciolfi, Giuseppe Anselmi, Niccolò Fattorini, Francesco Ferretti   +4 more
wiley   +1 more source