Results 111 to 120 of about 7,048,114 (301)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Design and optimization of a self-deploying single axis tracking PV array [PDF]
This study was performed in order to design a tracking photovoltaic (PV) array and optimize the design for maximum specific power. The design considerations were minimal deployment time, high reliability, and small stowage volume.
Colozza, Anthony J.
core +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Siting nuclear power plants in California: the near-term alternatives [PDF]
, 1973 There are many issues presently being debated concerning the generation and utilization of electric power in California. Some are peculiar to a specific area, such as the level of air quality and how it is influenced by fossil-fuel power plants.
Goldsmith, Martin
core
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Prospects for enhancing SEP array performance [PDF]
Three advanced blanket design models, all employing the OAST thin cell, were developed for potential incorporation into the SEP array. The beginning of life (BOL) specific power of the these blankets ranges from 180 to 660 W/kg.
Scott-Monck, J. A.
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Waste specific indicator at PWR and BWR nuclear power plants
Nuclear Engineering and TechnologyThe article shows the differences in the waste (hereinafter radioactive) specific indicators in the production of electricity at NPP of the two most common reactor installations types in the world PWR and BWR. The highest waste specific indicators values
V.A. Shatalin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Administrative Justice, Environmental Governance, and The Rule of Law in Malawi [PDF]
, 2019 This paper examines the impact of administrative law on the rule of law and governance in Malawi, using environmental agencies as a case study. Its findings expose a number of limitations of administrative law in facilitating good environmental ...
Banda, Chikosa
core +1 more source