High Specific Power Electrical Machines: A System Perspective [PDF]
There has been a growing need for high specific power electrical machines for a wide range of applications. These include hybrid/electric traction applications, aerospace applications and Oil and Gas applications.
EL-Refaie, Ayman M., Osama, Mohamed
core +1 more source
ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran+6 more
wiley +1 more source
Discussion: “Complete Pump Characteristics and the Effects of Specific Speeds on Hydraulic Transients” (Donsky, Benjamin, 1961, ASME J. Basic Eng., 83, pp. 685–696) [PDF]
Ignacy Swiecicki
openalex +1 more source
Kinetics of the helix-coil transition
Based on the Zimm-Bragg model we study cooperative helix-coil transition driven by a finite-speed change of temperature. There is an asymmetry between the coil-to-helix and helix-to-coil transition: the latter is displayed already for finite speeds, and ...
A. E. Allahverdyan+10 more
core +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
Discussion: “Measurement of the Unsteady and Cavitating Flow in a Model Francis Turbine of High Specific Speed” (Gerich, R., and Raabe, J., 1975, ASME J. Fluids Eng., 97, pp. 402–405) [PDF]
John F. Ripken
openalex +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Maximum Efficiency Despite Lowest Specific Speed—Simulation and Optimisation of a Side Channel Pump
Side channel pumps provide high pressure at relatively low flow rates. This comes along with a quite low specific speed and thus with the known disadvantage of a quite poor maximum efficiency.
Markus Mosshammer+3 more
doaj +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Influence of Tip Clearance on Pressure Fluctuation in Low Specific Speed Mixed-Flow Pump Passage
To explore the influence of tip clearance on pressure fluctuation in a low specific speed mixed-flow pump, tip clearances δ of 0.25 mm, 0.75 mm and 1.00 mm, along with no tip clearance, were selected.
Wenwu Zhang, Zhiyi Yu, Baoshan Zhu
doaj +1 more source