Results 151 to 160 of about 3,330,118 (346)

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Advanced turboprop technology development [PDF]

The efficiency of high-speed turboprop propulsion systems is considered with emphasis on fuel savings. Specific topics discussed include: (1) high efficiency and low noise of propeller design; (2) fuselage noise attenuation; (3) propeller and gear box ...
Bencze, D. P., Dugan, J. F., Williams, L. J.   +2 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Subcavitating performance of hydrofoils in accelerating cascade designed for high-specific-speed Kaplan-turbines. (1st Report. Suitable cascade hydrofoils of 3 percent in thickness).

, 1989
Tsutomu Narasaka, Risaburo OBA, Hitoshi SOYAMA, Johshiro Satoh, Yukihiko WADA, Seiichi TANABE   +5 more
openalex   +2 more sources

Unsteady Numerical Simulations of the Flow Related to the Unstable Energy-Discharge Characteristic of a Medium Specific Speed Double Suction Pump [PDF]

, 2007
O Braun, François Avellan, Philippe Dupont   +2 more
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

A Behavior of the Diffuser Rotating Stall in a Low Specific Speed Mixed-Flow Pump [PDF]

, 2009
Masahiro MIYABE, Akinori FURUKAWA, Hideaki Maeda, Isamu Umeki, Yoshinori Jittani   +4 more
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Performance Improvement in a Very Low Specific Speed Pump : Comparison between Closed Impeller and Semi-Open Impeller

, 2000
Mori Ishii, Junichi Kurokawa, Jun Matsui, Hiroshi IMAMURA, Kazunari Matsumoto   +4 more
openalex   +2 more sources

Influence of Different Performance Levels on Pacing Strategy During the Women's World Championship Marathon Race. [PDF]

Purpose To analyse pacing strategies displayed by athletes achieving differing levels of performance during an elite level marathon race. Methods Competitors in the 2009 IAAF Women’s Marathon Championship were split into Groups 1, 2, 3, and 4 ...
Renfree, Andrew, St Clair Gibson, Alan
core