Results 71 to 80 of about 3,330,118 (346)
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Response to automatic speed control in urban areas: A simulator study. [PDF]
Speed affects both the likelihood and severity of an accident. Attempts to reduce speed have centred around road design and traffic calming, enforcement and feedback techniques and public awareness campaigns.
Comte, S.L.
core
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
The optimization of a low specific speed pipeline pump
A low specific speed pipeline pump is researched to improve work performance through several certain modifications. The target is to raise the pump's head up to 80m and increase its total efficiency to 26.5% when the volume flow rate is 6.3m3/h with a rotatory speed of 2960rpm.
Dazhuan Wu, P Wu, L Q Wang, A Zhao
openaire +2 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
Long-Run Growth, Speed of Convergence and the Specification of Technology
Abstract This note analyzes the effect that the specification of technology has on the long-run growth rate and the asymptotic speed of convergence in the one-sector endogenous-growth model. We compare three otherwise identical economies – with the same baseline and parameter values – but with different production technologies: CES, VES ...
openaire +3 more sources
High-speed data word monitor [PDF]
Small, portable, self-contained device provides high-speed display of bit pattern or any selected portion of transmission, can suppress filler patterns so that display is not updated, and can freeze display so that specific event may be observed in ...
Wirth, M. N.
core +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source
Particle methods parallel implementations by GP-GPU strategies [PDF]
This paper outlines the problems found in the parallelization of SPH (Smoothed Particle Hydrodynamics) algorithms using Graphics Processing Units.
Cercós Pita, Jose Luis+3 more
core +1 more source