Results 81 to 90 of about 3,330,118 (346)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

On the Rotor Stator Interaction Effects of Low Specific Speed Francis Turbines

open access: yesInternational Journal of Rotating Machinery, 2019
The rotor stator interaction in a low specific speed Francis model turbine and a pump-turbine is analyzed utilizing pressure sensors in the vaneless space and in the guide vane cascade.
Einar Agnalt   +3 more
doaj   +1 more source

On constraining the speed of gravitational waves following GW150914

open access: yes, 2016
We point out that the observed time delay between the detection of the signal at the Hanford and Livingston LIGO sites from the gravitational wave event GW150914 places an upper bound on the speed of propagation of gravitational waves, $c_{gw}\lesssim 1 ...
Blas, Diego   +3 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

CFD-Based Investigation of the Operation Process of Radial Labyrinth Machinery Under Different Geometrical Configurations

open access: yesEnergies
This study explores the performance and flow characteristics of radial labyrinth pumps (RLPs) under various geometrical configurations and operating conditions.
Przemyslaw Szulc, Janusz Skrzypacz
doaj   +1 more source

First order ball bearing kinematics [PDF]

open access: yes
Two first order equations are given connecting geometry and internal motions in an angular contact ball bearing. Total speed, kinematic equivalence, basic speed ratio, and modal speed ratio are defined and discussed; charts are given for the speed ratios
Kingbury, E.
core   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Estimating Workforce Development Needs for High-Speed Rail in California, Research Report 11-16 [PDF]

open access: yes, 2012
This study provides an assessment of the job creation and attendant education and training needs associated with the creation of the California High-Speed Rail (CHSR) network, scheduled to begin construction in September 2012.
Estrada, Katherine   +2 more
core   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Configuration blade shape for enhancement crossflow turbine performance by the CFD method

open access: yesInternational Journal of Thermofluids
The pico scale crossflow turbine (CFT) is a prospect as an independent power plant for remote and rural areas because it has a stable efficiency range of 64 % to 79.5 % in high discharge fluctuation.
Dendy Adanta   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy