Objective The objective of this study was to estimate the minimal important change (MIC) and minimal clinically important difference (MCID) for pain and physical function in individuals with hip osteoarthritis (OA) following a physiotherapist‐guided exercise intervention.
Yareni Guerrero +8 more
wiley +1 more source
Distribution-based covariate assessment using wasserstein distance in population pharmacokinetic models. [PDF]
Simon N, Hulot JS, von Fabeck K.
europepmc +1 more source
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source
From study design to executable code: automating target trial emulation with large language models. [PDF]
Kim H, Kim M, Kim S, You SC.
europepmc +1 more source
High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello +5 more
wiley +1 more source
Comment on Lahoud et al. Burden and Mortality Outcomes of <i>Clostridioides difficile</i> Infection Among Patients with Chronic Obstructive Pulmonary Disease: Findings from a Nationwide Database. <i>J. Clin. Med.</i> 2026, <i>15</i>, 4110. [PDF]
Cohen BD.
europepmc +1 more source
Trajectories of Physical Function in Canadian Children With Juvenile Idiopathic Arthritis
Objective We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham +81 more
wiley +1 more source
Floral identity and beyond: revisiting AGAMOUS-like transcription factor functions in rice. [PDF]
Brazel AJ.
europepmc +1 more source
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli +10 more
wiley +1 more source
TRACE: A Framework for Integrating Transcript Relevance Into ACMG/AMP Variant Interpretation. [PDF]
Goel H.
europepmc +1 more source

