Results 51 to 60 of about 1,814,894 (278)
Export of miRNAs from activated macrophages is cooperative and HuR‐dependent
FEBS Letters, EarlyView.This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh +2 more
wiley +1 more source
Siriraj Medical Journal, 2018 Objective: The aim of this study was to find a technique to make a disposable monofilament which is accurate and affordable for Thailand context. A prototype of local made monofilament was developed and tested with the calibrated universal machine test
Danu Prommin, Ph.D. +6 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
British Medical Bulletin, 2000 The prevalence of atopic allergic disease increased substantially towards the end of the 20th century and is set to rise further. This group of diseases now constitutes the most common cause of chronic ill health in industrialised countries. Despite considerable attention from the pharmaceutical industry, little progress has been made in the ...
openaire +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Market dynamics and future prospects of the automobile industry in Saudi Arabia [PDF]
Problems and Perspectives in Management, 2018 As the Kingdom of Saudi Arabia focuses on Vision 2030, there is an immediate need to establish some big manufacturing industries to create jobs and to generate revenue from non-oil sectors.
Mohammad Rumzi Tausif +1 more
doaj +1 more source
Scalability using effects [PDF]
, 2013 This note is about using computational effects for scalability. With this method, the specification gets more and more complex while its semantics gets more and more correct.
Duval, Dominique
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
La concesividad como complemento argumental: Pragmática i gramática comparada en asturiano y castellano [PDF]
Sintagma, 2008 Asturian grammar distinguishes semantic references of mass and individual nouns by means of agreement with adjectives and clitics. But the morphological category of mass neuter in Asturian also develops in utterances a sophisticated specification system ...
Xulio Viejo Fernández
doaj
Scratch-Based User-Friendly Requirements Definition for Formal Verification of Control Systems
Informatics in Education, 2020 Control systems are becoming ever more commonly used in everyday life. This is true both in industry and in the domestic domain, in the form of e.g., smart home systems.
Iwona GROBELNA
doaj +1 more source