Results 91 to 100 of about 4,525,804 (339)
FEBS Letters, EarlyView.Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Coexistence of critical sensitivity and subcritical specificity can yield optimal population coding
, 2017 The vicinity of phase transitions selectively amplifies weak stimuli, yielding optimal sensitivity to distinguish external input. Along with this enhanced sensitivity, enhanced levels of fluctuations at criticality reduce the specificity of the response.
Gollo, Leonardo L.
core +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Di-san junyi daxue xuebao, 2019 Objective To detect the expression of high mobility group box 1 (HMGB1) in hemophagocytic lymphohistiocytosis (HLH) patients and explore its clinical significance in the disease.
CHEN Ying +4 more
doaj +1 more source
Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity [PDF]
, 2010 TRIMCyps are anti-retroviral proteins that have arisen independently in New World and Old World primates. All TRIMCyps comprise a CypA domain fused to the tripartite domains of TRIM5α but they have distinct lentiviral specificities, conferring HIV-1 ...
A Katzourakis +62 more
core +5 more sources
Journal of Investigative Dermatology, 1970 The present study was undertaken to ascertain whether regional dermal specificity could be demonstrated at the molecular level. Dermis was obtained from the following areas of White Leghorn roosters: comb, wattle, trunk (feathers), leg (scales) and ear lobes.
Fleischmajer, Raul, Krol, Stefan
openaire +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Systematic review and meta-analysis of the diagnostic accuracy of ultrasonography for deep vein thrombosis [PDF]
, 2005 Background Ultrasound (US) has largely replaced contrast venography as the definitive diagnostic test for deep vein thrombosis (DVT). We aimed to derive a definitive estimate of the diagnostic accuracy of US for clinically suspected DVT and identify ...
A Cogo +133 more
core +5 more sources
Acupuncture: Specific and Non-Specific Effects [PDF]
Forschende Komplementärmedizin / Research in Complementary Medicine, 2008 As an alternative and complement to conventional or allopathic medicine, acupuncture has become a firmly established therapy in many countries. Despite this wide acceptance, the question of how acupuncture works, or whether it works at all, remains the subject of lively debate. One problem in the discussion of acupuncture and its possible mechanisms is
openaire +3 more sources