Results 91 to 100 of about 2,010,640 (293)

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Sodium butyrate attenuates oxidative stress, apoptosis, and excessive mitophagy in sodium fluoride-induced hepatotoxicity in rats

Ecotoxicology and Environmental Safety
Aim: Long-term exposure to excess sodium fluoride (NaF) can cause chronic fluorosis. Liver, the most important detoxification organ, is the most vulnerable to the effects of fluoride.
Jing Xia, Xiaolin Zhang, Leiyu Xu, Nan Yan, Zhenxiang Sun, Xiaoxu Duan, Lu Meng, Rong Qi, Fu Ren, Zhengdong Wang   +9 more
doaj  

Interaction between Shiga Toxin and Monoclonal Antibodies: Binding Characteristics and in Vitro Neutralizing Abilities

Toxins, 2012
Monoclonal antibodies (MAbs) have been employed either for diagnosis or treatment of infections caused by different pathogens. Specifically for Shiga toxin-producing Escherichia coli (STEC), numerous immunoassays have been developed for STEC diagnosis ...
Letícia B. Rocha, Daniela E. Luz, Claudia T. P. Moraes, Andressa Caravelli, Irene Fernandes, Beatriz E. C. Guth, Denise S. P. Q. Horton, Roxane M. F. Piazza   +7 more
doaj   +1 more source

Requirements, Formal Verification and Model transformations of an Agent-based System: A CASE STUDY [PDF]

arXiv, 2015
One of the most challenging tasks in software specifications engineering for a multi-agent system is to ensure correctness. As these systems have high concurrency, often have dynamic environments, the formal specification and verification of these systems along with step-wise refinement from abstract to concrete concepts play major role in system ...
arxiv  

Dynamic Specification

, 2000
AbstractThis survey provides a route map, sketching the major issues, models, concepts, and techniques. A taxonomy of model types is presented, each being examined for advantages and drawbacks as a generic form. Exogeneity and the overall model reduction framework are described.
Hendry, D, Pagan, A, Sargan, J
openaire   +4 more sources

Acupuncture: Specific and Non-Specific Effects [PDF]

Forschende Komplementärmedizin / Research in Complementary Medicine, 2008
As an alternative and complement to conventional or allopathic medicine, acupuncture has become a firmly established therapy in many countries. Despite this wide acceptance, the question of how acupuncture works, or whether it works at all, remains the subject of lively debate. One problem in the discussion of acupuncture and its possible mechanisms is
openaire   +3 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Improving hemodialysis patient depression outcomes with acupuncture: A randomized controlled trial

Acta Psychologica
Objective: To evaluate the efficacy and safety of acupuncture as a supplementary treatment for mild to moderate depression in hemodialysis patients. Method: This multicenter, randomized, controlled, single-masked trial included 64 hemodialysis patients ...
Xijing Yu, Shuisheng Hua, Engyu Jin, Rong Guo, Hui Huang   +4 more
doaj  

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source