Results 161 to 170 of about 4,678,205 (343)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

A Study of Non-specific Stress Indicators and Skeletal Growth in Two Mediaeval Subadult Populations

, 1996
Isabelle Ribot, Charlotte A. Roberts
openalex   +2 more sources

Sister chromatid interactions in bacteria revealed by a site‐specific recombination assay [PDF]

, 2012
Christian Lesterlin, Emmanuelle Gigant, Frédéric Boccard, Olivier Espéli   +3 more
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

“On demand” redox buffering by H₂S contributes to antibiotic resistance revealed by a bacteria-specific H₂S donor

, 2017
Prashant Shukla, Vinayak S. Khodade, Sharath Chandra Mallojjala, Preeti Chauhan, Saurabh Mishra, Shivakumara Siddaramappa, Eswarappa Pradeep Bulagonda, Amit Singh, Harinath Chakrapani   +8 more
openalex   +2 more sources

Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA repair and tumor growth [PDF]

, 2017
Jinping Liu, Alex Kruswick, Hien Dang, Andy D. Tran, So Mee Kwon, Xin Wei Wang, Philipp Oberdoerffer   +6 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

PIWI genes and piRNAs are ubiquitously expressed in mollusks and show patterns of lineage-specific adaptation

, 2018
Julia Jehn, Daniel Gebert, Frank Pipilescu, Sarah Stern, Julian Simon Thilo Kiefer, Charlotte Hewel, David Rosenkranz   +6 more
openalex   +1 more source

ELF5 isoform expression is tissue-specific and significantly altered in cancer [PDF]

, 2016
Catherine Piggin, Daniel Roden, David Gallego‐Ortega, Heather Lee, Samantha R. Oakes, Christopher J. Ormandy   +5 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source