Results 191 to 200 of about 2,080,270 (249)

Efficacy and limitations of a web-based native adult knee septic arthritis calculator in urban trauma care. [PDF]

OTA Int
Serbin RP, Burger J, Odum S, Chandler C, Welch S, Di Napoli N, Duncan A, Wally MK, Lack W, Karunakar M, Seymour RB, Evidence-Based Musculoskeletal Injury and Trauma Collective (EMIT) .   +11 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Clinical setting-dependent diagnostic accuracy of artificial intelligence and store-and-forward diabetic retinopathy screening: a systematic review and meta-analysis. [PDF]

NPJ Digit Med
Chen KY, Chan HC, Chan CM.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Comparison of the effectiveness of RIPASA and modified Alvarado scores in identifying perforated appendicitis. [PDF]

Ulus Travma Acil Cerrahi Derg
Kamburoğlu A, Çimen Ş, Uçaner B, Buldanlı MZ, Hançerlioğullari O.   +4 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Correction to "Pre-Treatment Serum Prognostic Scores and Survival in Curatively Treated Laryngeal Cancer". [PDF]

Laryngoscope Investig Otolaryngol
europepmc   +1 more source

The impact of right ventricular free wall strain on current international echocardiography guidelines for the assessment of pulmonary hypertension. [PDF]

Echo Res Pract
Wild CJB, Coghlan G, Charalampopoulos A, Hameed A, Suntharalingam J, Ross RM, Knight D, Willis J, Page J, Gurung A, Johnson M, Karia N, Oxborough D, Peacock O, Thompson D, Augustine DX.   +15 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Biomarkers stewardship in parkinsonism: integrating alpha-synuclein seed amplification assays and neurofilament light chain into diagnostic pathways and patient communication. [PDF]

J Neurol
Leclercq V.
europepmc   +1 more source