Results 221 to 230 of about 4,678,205 (343)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Global Bivariate Meta-Analysis of FIB-4 Cut-Offs to Rule Out Advanced Fibrosis in MASLD. [PDF]

Int J Hepatol
Ghosal A, Ghosal S.
europepmc   +1 more source

Defining the optimal approach to the patient with postradiation prostate‐specific antigen recurrence using outcome data from a prospective randomized trial [PDF]

, 2013
Miranda B. Kim, Ming‐Hui Chen, Mário de Castro, Marian Loffredo, Philip W. Kantoff, Anthony V. D’Amico   +5 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Phospholipid Profiling Established by Structure-Rich Fragments for Molecular Species Level Shotgun Analysis. [PDF]

Rapid Commun Mass Spectrom
Chen R, Jannasch AH, Cooper BR, Shannahan JH, Ferreira CR.   +4 more
europepmc   +1 more source

Loss of endothelial cell-specific molecule 1 promotes the tumorigenicity and metastasis of prostate cancer cells through regulation of the TIMP-1/MMP-9 expression

, 2017
Chien‐Min Chen, Chu‐Liang Lin, Hui‐Ling Chiou, Shu-Ching Hsieh, Chia‐Liang Lin, Chun‐Wen Cheng, Chia‐Hung Hung, Jen‐Pi Tsai, Yi‐Hsien Hsieh   +8 more
openalex   +2 more sources

Altered fractalkine cleavage results in an organ-specific 17 kDa fractalkine fragment in salivary glands of NOD mice [PDF]

, 2008
Nicolas Delaleu, Roland Jonsson
openalex   +1 more source

Does Gender Specificity in Constitutions Matter? [PDF]

, 2009
Lucas, Laura E.
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

<i>KRAS</i> Mutations in Circulating Tumor DNA for Lung Cancer Diagnosis: A Comprehensive Meta-Analysis. [PDF]

Cancers (Basel)
Buszka K, Gąsiorowski Ł, Dompe C, Szulta A, Nowicki M, Kolecka-Bednarczyk A, Budna-Tukan J.   +6 more
europepmc   +1 more source