Results 221 to 230 of about 2,535,115 (299)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Diagnostic test accuracy meta-analysis of transcranial motor evoked potential monitoring for the prediction of postoperative neurological deficits in ossification of the posterior longitudinal ligament surgery. [PDF]

Clin Neurophysiol Pract
Velur Prasuna L, Vibha V, Marvin G.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Validation of a Pregnancy-Associated Glycoprotein-Based Lateral Flow Assay for Early Pregnancy Detection in Goats. [PDF]

Vet Med Sci
Kara MC, Köse AM.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Diagnosis of Prostate Cancer: A Comparative Evaluation of Biological Techniques. [PDF]

Diseases
Tshoni UA, Mbonane TP, Rathebe PC.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Specificity of diatom Rubisco

, 2005
Haslam, R. P., Alfred J. Keys, Parry, M. A. J., Anette Grimsrud, Andersson Inger, Pippa J. Madgwick, Eilertsen, H. C., P John Andralojc, Andralojc, P. J., Hans C. Eilertsen, Martin A. J. Parry, Grimsrud, A., Richard P. Haslam, Madgwick, P. J., Andersson, I., Keys, A. J.   +15 more
core   +1 more source

Identification of a capsid-derived Zika virus epitope with high IgG discriminatory performance. [PDF]

Arch Virol
Dos Santos ALC, Lopes SR, Amaral RP, Malaquias LCC, Dos Santos Nunes Ferreira A, de Oliveira DB, Coelho LFL.   +6 more
europepmc   +1 more source

A Specification Translation from Behavioral Specifications to Rewrite Specifications

A Specification Translation from Behavioral Specifications to Rewrite Specifications
There are two ways to describe a state machine as an algebraic specification: a behavioral specification and a rewrite specification. In this study, we propose a translation system from behavioral specifications to rewrite specifications to obtain a verification system which has the strong points of verification techniques for both specifications ...
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