Results 141 to 150 of about 593,446 (298)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Peculiarities of Russian nicknames’ inner form
Considering word-forming possibilities of Russian nicknames from the point of view of their national peculiarities marked process. It is established that two basic groups of factors extralinguistic and innerlinguistic influence the development and ...
Marina Yurevna MOROZOVA
doaj
Tissue-specific and species-specific esterases [PDF]
J, PAUL, P, FOTTRELL
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Specifics of covering migration problems in regional printed mass media
The problem of creating an image of forced migrants in Russian regional printed mass media has been discussed. The articles on migration problems that were published in the newspapers “Nash Zelenyi Dol” and “Zelenodol'skaya Pravda” during the period of ...
A.Yu. Anisimov, D.V. Tumanov
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The specifics of criminalistic activity in criminal judicial process
The paper defines the concept, essence, means, and subjects of criminalistic activity in criminal judicial process. The criminalistic activity in criminal judicial process is a complex of purposeful and regulatory proving activities performed by court ...
A.V. Mishin
doaj

