Results 201 to 210 of about 593,446 (298)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Navigating recurrent <i>Clostridioides difficile</i> infection without Bezlotoxumab: potential challenges ahead. [PDF]
Antimicrob Steward Healthc EpidemiolArya R, Zimmet AN, Holubar M, Alegria W.
europepmc +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Sex-specific anatomical challenges in TAVR: A closer look at bicuspid aortic valve stenosis. [PDF]
Int J Cardiol Cardiovasc Risk PrevHuang P +7 more
europepmc +1 more source
A Specification Translation from Behavioral Specifications to Rewrite Specifications
A Specification Translation from Behavioral Specifications to Rewrite SpecificationsThere are two ways to describe a state machine as an algebraic specification: a behavioral specification and a rewrite specification. In this study, we propose a translation system from behavioral specifications to rewrite specifications to obtain a verification system which has the strong points of verification techniques for both specifications ...
openaire
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Guest Editor Introduction: International Patellofemoral Study Group Special Issue. [PDF]
Video J Sports MedDiduch DR, Sherman SL, Yanke A.
europepmc +1 more source
A Specification Translation from behavioral Specification to rewrite Specifications
A Specification Translation from behavioral Specification to rewrite SpecificationsThere are two ways to describe a state machine as an algebraic specification: a behavioral specification and a rewrite specification. In this study, we propose a translation system from behavioral specifications to rewrite specifications to obtain a verification system which has the strong points of verification techniques for both specifications ...
openaire
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source