Results 231 to 240 of about 593,446 (298)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Density Dependence Promotes Species Coexistence and Provides a Unifying Explanation for Distinct Productivity-Diversity Relationships. [PDF]

Ecol Lett
Xu L, Klausmeier CA, Zakem E.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cognitive understanding is a functional coordination pattern, just like swimming. [PDF]

Front Psychol
De Jonge-Hoekstra L.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Enoxaparin Dosing and Target anti-Factor Xa Achievement in Infants by Postmenstrual Age. [PDF]

J Pediatr Pharmacol Ther
Perez D, Mathew K.
europepmc   +1 more source

Gastric Squamous Cell Carcinoma as a Cause of Clinically Unstable Gastrointestinal Bleeding. [PDF]

ACG Case Rep J
Moore T, Martinez-Uribe O, Guy CD, Johnson A, Lee J.   +4 more
europepmc   +1 more source

Clinical characterization of IRF2BPL mutation: Case series and review of the literature. [PDF]

Medicine (Baltimore)
Lou X, Li W, Pang M, Wang Y, Zhu X, Geng J.   +5 more
europepmc   +1 more source

Authors' response to letter to the Editor from Aphale, P, et al., Resident autonomy in pathology: bridging gaps between training and practice. [PDF]

Acad Pathol
Bryant BH, Puligandla B, Gosnell HL, Johnson K, Barak S, Berg MP, Karp JK, Lofgreen A, McCloskey CB, Knollmann-Ritschel BEC, White KL, Black-Schaffer WS.   +11 more
europepmc   +1 more source