Results 41 to 50 of about 593,446 (298)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Questions of Research of Digitalization in Various Fields of Activity

open access: yesЦифровая трансформация
The ability to implement strategic priorities of digital development and intensify the activities of various stakeholders (government, science, business, enterprises) in high-tech sectors are necessary conditions for the successful development of the ...
N. O. Yakushev
doaj   +1 more source

Specifics of military leadership [PDF]

open access: yesMegatrend Revija
The paper starts from consideration of the theoretical basis of leadership, as well as its relationship with management as a basic approach in managing the organization, in order to arrive at a certain definition of military leadership. Leadership exists
Hatidža Beriša, Barišić Igor
doaj   +1 more source

Specificity Distinctions

open access: yesJournal of Semantics, 2001
This paper is concerned with semantic noun phrase typology, focusing on the question of how to draw fine-grained distinctions necessary for an accurate account of natural language phenomena. In the extensive literature on this topic, the most commonly encountered parameters of classification concern the semantic type of the denotation of the noun ...
openaire   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

SPECIFICS OF MATHEMATICS EDUCATION FUTURE ENGINEERS NUCLEAR INDUSTRY

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2015
The work is devoted to study the specifics of the mathematical education of future engineers of the nuclear industry. Determined the basic tasks of mathematical preparation of students, identified the main principles of its organization.
Georgy M. Il’mushkin   +1 more
doaj  

Specifics sociological analisis crimes

open access: yesВісник НЮУ імені Ярослава Мудрого: Серія: Філософія, філософія права, політологія, соціологія, 2016
The article notes that today the crime hit all spheres of Ukrainian society. In this regard, it is important to study in depth the nature, causes, effects and trends of this social phenomenon, which has both scientific and practical significance.
В. Д. Воднік
doaj   +1 more source

Specifics about Specific Ion Adsorption from Heterodyne-Detected Second Harmonic Generation

open access: yes, 2019
Ion specific outcomes at aqueous interfaces remain among the most enigmatic phenomena in interfacial chemistry. Here, charged fused silica/water interfaces have been probed by homodyne- and heterodyne-detected (HD) second harmonic generation (SHG ...
Boamah, Mavis D.   +4 more
core   +2 more sources

A domain-specific language for the specification of UCON policies

open access: yesJournal of Information Security and Applications, 2022
Ministerio de Ciencia e Innovación LOCOSS - PID2020-114615RB ...
Reina Quintero, Antonia M.   +4 more
openaire   +4 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

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