Results 201 to 210 of about 1,376,572 (293)

Programmable Information Processing With Reconfigurable Self‐Contact Variable Stiffness Mechanical Metamaterial

open access: yesAdvanced Science, EarlyView.
Reconfigurable self‐contact variable stiffness metamaterials based on shape memory polymers enable programmable stiffness switching. Static arrays store and encrypt information with immunity to electromagnetic interference, while asymmetric stiffness converts symmetric vibration into directional matter transport.
Huadong Qin   +7 more
wiley   +1 more source

Eight quick tips for requesting materials from natural history collections. [PDF]

open access: yesPLoS Comput Biol
Scorsim Omura GY   +2 more
europepmc   +1 more source

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang   +14 more
wiley   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang   +17 more
wiley   +1 more source

Point-of-care routine laboratory testing for patients with suspected viral hemorrhagic fevers. [PDF]

open access: yesAntimicrob Steward Healthc Epidemiol
Sullivan AL   +10 more
europepmc   +1 more source

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

open access: yesAdvanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu   +12 more
wiley   +1 more source

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