Results 201 to 210 of about 1,274,575 (296)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

Development and validation of a Dor fundoplication simulator. [PDF]

open access: yesJTCVS Open
Tasnim S   +7 more
europepmc   +1 more source

A Smart Fluid‐Hydraulic System Based on MRF Valve Control and Its Application in Flexible Grasping

open access: yesAdvanced Science, EarlyView.
This study introduces a smart fluid hydraulic system using MRF valve control for flexible gripping. An MRF‐MSV with an integrated excitation coil and micro‐textured damping channels is designed and validated; micro‐texturing increases hydraulic resistance. Coupled with a soft actuator, the MRF‐MSV enables dynamic bending and grasping.
Linfeng Huo   +5 more
wiley   +1 more source

Label‐Free Myelin Fingerprinting: An Adult Human Post‐Mortem Brain Slice Platform via Coherent Anti‐Stokes Raman Spectroscopy

open access: yesAdvanced Science, EarlyView.
A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki   +5 more
wiley   +1 more source

Analysis of purines and pyrimidines across biospecimens: influence of storage temperature and duration. [PDF]

open access: yesSci Rep
Wurth R   +9 more
europepmc   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong   +13 more
wiley   +1 more source

Real‐Time Ferroelectric Domain Wall Dynamics During Electric Poling and Depoling

open access: yesAdvanced Science, EarlyView.
Real‐time visualization of domain wall dynamics during alternating‐current poling, direct‐current poling, and electrical depoling in relaxor‐PT ferroelectric single crystals reveals distinct field‐dependent pathways and strong path dependence. Instant polarized light microscopy uncovers reversible domain wall nucleation, motion, and reconfiguration ...
Ziqi Wang   +12 more
wiley   +1 more source

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