Results 51 to 60 of about 215,329 (365)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Practical Understanding of Gross Examination Techniques

open access: yesKorean Journal of Clinical Laboratory Science
Gross examination techniques (GETs) of specimens collected from cancer surgery or endoscopy comprise the act of recording visual information about cancer for accurate histopathological diagnosis and collecting sections of the lesion to create microscopic
Woo-Hyun JI
doaj   +1 more source

Reliable measurement of plasma kinin peptides: Importance of preanalytical variables

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2022
Background The kallikrein‐kinin system is involved in many (patho)physiological processes and kinin peptides are considered potential clinical biomarkers.
Tanja Gangnus, Bjoern B. Burckhardt
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

open access: yesAdvanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang   +6 more
wiley   +1 more source

Extensive comparison of salivary collection, transportation, preparation, and storage methods: a systematic review

open access: yesBMC Oral Health
Background Human saliva as a bodily fluid—similar to blood—is utilized for diagnostic purposes. Unlike blood sampling, collecting saliva is non-invasive, inexpensive, and readily accessible.
Hamed Mortazavi   +2 more
doaj   +1 more source

Frequently asked questions about coronavirus (COVID-19) for laboratories [PDF]

open access: yes
Updated July 16, 2020Accessing Laboratory Testing -- Test Developers -- Serology -- Specimen Handling -- Specimen Packing and Shipping -- Specimen Types -- Anatomic Pathology -- Ordering Supplies (For Public Health Laboratories) -- Ordering Supplies (For

core   +9 more sources

Interim guidelines for collecting and handling of clinical specimens for COVID-19 testing [PDF]

open access: yes
Updated July 15, 2022Collecting and Handling Specimens Safely -- Respiratory Specimen Collection -- Assessing Validity of Specimens Obtained Through Self-Collection -- Handling Bulk-Packaged Sterile Swabs Properly for Upper Respiratory Specimen ...

core   +3 more sources

Quasicontinuum Method Extended to Irregular Lattices [PDF]

open access: yes, 2017
The quasicontinuum (QC) method, originally proposed by Tadmor, Ortiz and Phillips in 1996, is a computational technique that can efficiently handle regular atomistic lattices by combining continuum and atomistic approaches. In the present work, the QC method is extended to irregular systems of particles that represent a heterogeneous material.
arxiv   +1 more source

Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast [PDF]

open access: yes, 2014
Background: The Sloane Project is the largest prospective audit of ductal carcinoma in situ (DCIS) worldwide, with over 12000 patients registered between 2003 and 2012, accounting for 50% of screen-detected DCIS diagnosed in the UK over the period of ...
,   +11 more
core   +1 more source

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