Results 111 to 120 of about 3,214,745 (368)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Different methods for characterizing surface roughness using laser speckle technique

open access: yesIraqi Journal of Physics, 2019
In this work, results from an optical technique (laser speckle technique) for measuring surface roughness was done by using statistical properties of speckle pattern from the point of view of computer image texture analysis.
Mayada B. Al-Quzweny
doaj   +1 more source

Application of laser speckle contrast imaging in laparoscopic surgery.

open access: yesBiomedical Optics Express, 2019
Anastomotic leakage is a worldwide problem in gastrointestinal surgery which seems to be related to the state of microcirculation. Laser speckle contrast imaging (LSCI) could give surgeons insight in the state of microcirculation to attune the site of ...
W. Heeman   +6 more
semanticscholar   +1 more source

Speckle Statistics in Adaptively Corrected Images

open access: yes, 2005
(abridged) Imaging observations are generally affected by a fluctuating background of speckles, a particular problem when detecting faint stellar companions at small angular separations.
Aime C.   +13 more
core   +1 more source

PeX 1. Multi-spectral expansion of residual speckles for planet detection [PDF]

open access: yes, 2017
The detection of exoplanets in coronographic images is severely limited by residual starlight speckles. Dedicated post-processing can drastically reduce this "stellar leakage" and thereby increase the faintness of detectable exoplanets.
Devaney, Nicholas, Thiébaut, Éric
core   +2 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Speckle Control with a remapped-pupil PIAA-coronagraph

open access: yes, 2012
The PIAA is a now well demonstrated high contrast technique that uses an intermediate remapping of the pupil for high contrast coronagraphy (apodization), before restoring it to recover classical imaging capabilities.
Belikov R.   +10 more
core   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Assessment of microcirculation in the diabetic foot with laser speckle contrast imaging

open access: yesPhysiological Measurement, 2019
Objective: A major challenge for treating diabetic foot ulcers is estimating the severity of ischemia, as the currently used non-invasive diagnostic techniques provide relatively poor prognostic values.
O. A. Mennes   +3 more
semanticscholar   +1 more source

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