Results 191 to 200 of about 6,108,061 (222)

Enhancement of the Optoelectric and Photovoltaic Responses of Al/PVP:ZnTiO3/p‐Si Structure by Graphene Nanoparticles

open access: yesAdvanced Photonics Research, EarlyView.
This study investigates the optoelectronic response of Al/p‐Si photodiodes with and without a (PVP:Gr‐ZnTiO3) interlayer under varying light intensities. Key parameters are analyzed, revealing that the interlayer enhances photosensitivity, optical responsivity, and specific detectivity.
Ali Barkhordari   +5 more
wiley   +1 more source

In vivo Terahertz Sensing of Skin Cancer Patients

open access: yesAdvanced Photonics Research, EarlyView.
This study presents the first in vivo measurements of skin cancer patients in a hospital setting using a handheld THz probe. Furthermore, a new analysis approach is developed to generate a patient‐normalized THz response function, which enables clear contrast to be seen between cancer and healthy skin of the same patient.The first in vivo study of skin
Jacob J. Young   +4 more
wiley   +1 more source

Machine Learning Techniques for Simulating Human Psychophysical Testing of Low‐Resolution Phosphene Face Images in Artificial Vision

open access: yesAdvanced Science, EarlyView.
To evaluate the quality of artificial visual percepts generated by emerging methodologies, researchers often rely on labor‐intensive and tedious human psychophysical experiments. The present work investigates the capacity of standard machine learning models to accurately replicate quaternary match‐to‐sample tasks using low‐resolution facial images ...
Na Min An   +4 more
wiley   +1 more source

Activation of Glutamatergic Neurons in the Supramammillary Nucleus Promotes the Recovery of Consciousness under Sevoflurane Anesthesia

open access: yesAdvanced Science, EarlyView.
Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li   +8 more
wiley   +1 more source

Interpretable Multimodal Fusion Model for Bridged Histology and Genomics Survival Prediction in Pan‐Cancer

open access: yesAdvanced Science, EarlyView.
This article introduces the Brim model, an interpretable multimodal fusion framework that integrates histopathology, genomics, and transcriptomics to enhance cancer prognosis prediction. Addressing real‐world data limitations, the model enables precise predictions even with incomplete molecular data.
Feng Gao   +9 more
wiley   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu   +13 more
wiley   +1 more source

Epithelial Cell Mechanoresponse to Matrix Viscoelasticity and Confinement Within Micropatterned Viscoelastic Hydrogels

open access: yesAdvanced Science, EarlyView.
Extracellular matrix (ECM) viscoelasticity and spatial confinement regulate cellular processes such as cancer progression, yet their interplay remains poorly understood. By developing fibronectin (FN)‐micropatterned viscoelastic hydrogels mimicking breast cancer mechanics, this study explores breast epithelial cell mechanoresponse to ECM ...
Giuseppe Ciccone   +6 more
wiley   +1 more source

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

open access: yesAdvanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang   +16 more
wiley   +1 more source

Wearable Systems of Reconfigurable Microneedle Electrode Array for Subcutaneous Multiplexed Recording of Myoelectric and Electrochemical Signals

open access: yesAdvanced Science, EarlyView.
A reconfigurable microneedle electrode array integrated system is developed for minimally invasive and transdermal monitoring of subcutaneous electromyography, reactive oxygen species, and pH values. By assembling discrete thumbtack‐shaped microneedles into an array, the system enables multi‐parameter detection with single‐microneedle resolution.
Zhengjie Liu   +12 more
wiley   +1 more source

Oral Microalgae‐Based Biosystem to Enhance Irreversible Electroporation Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study presents an innovative oral microalgae‐based biosystem to inhibit tumor growth, reduce PD‐1 expression, and activate immune responses of hepatocellular carcinoma. When combined with enhanced irreversible electroporation treatment, it demonstrates a synergistic effect that effectively reduces the tumor burden and enhances the tumor immune ...
Cheng Zeng   +8 more
wiley   +1 more source

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