Results 31 to 40 of about 6,108,061 (222)

Intraoperative multi-exposure speckle imaging of cerebral blood flow

Journal of Cerebral Blood Flow and Metabolism, 2017
Multiple studies have demonstrated that laser speckle contrast imaging (LSCI) has high potential to be a valuable cerebral blood flow monitoring technique during neurosurgery.
L. Richards, S. S. Kazmi, Katherine E. Olin, J. Waldron, Douglas Fox, A. Dunn   +5 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Speckle Temporal Stability in eXtreme Adaptive Optics Coronagraphic Images [PDF]

, 2012
The major noise source limiting high-contrast imaging is due to the presence of quasi-static speckles. Speckle noise originates from wavefront errors caused by various independent sources, and it evolves on different timescales pending to their nature.
arxiv   +1 more source

Use of kurtosis for locating deep blood vessels in raw speckle imaging using a homogeneity representation

Journal of Biomedical Optics, 2017
. Visualization of deep blood vessels in speckle images is an important task as it is used to analyze the dynamics of the blood flow and the health status of biological tissue.
H. Peregrina-Barreto, Elizabeth Perez-Corona, J. Rangel-Magdaleno, R. Ramos-García, R. Chiu, J. Ramirez-San-Juan   +5 more
semanticscholar   +1 more source

Establishment and biological characterization of radioresistant colorectal cancer cell lines

FEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu, Qing Dai, Jing Leng, Lin Fang, Jing‐Jing Ma, Rui Chen, Che Chen, Peng‐Fei Ran, Wen‐Wen Zhou, Chang Liu, Huang‐Fei Yu   +10 more
wiley   +1 more source

Purely Speckled Intensity Images Need for SAR Despeckling with SDS-SAR [PDF]

arXiv, 2023
Speckle noise is generated along with the SAR imaging mechanism and degrades the quality of SAR images, leading to difficult interpretation. Hence, despeckling is an indispensable step in SAR pre-processing. Fortunately, supervised learning (SL) has proven to be a progressive method for SAR image despeckling.
arxiv  

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

The Role of Laser Speckle Imaging in Port-Wine Stain Research: Recent Advances and Opportunities

IEEE Journal of Selected Topics in Quantum Electronics, 2016
Here, we review our current knowledge on the etiology and treatment of port-wine stain (PWS) birthmarks. Current treatment options have significant limitations in terms of efficacy. With the combination of 1) a suitable preclinical microvascular model, 2)
Bernard Choi, W. Tan, W. Jia, Sean M. White, Wesley J. Moy, Bruce Y. Yang, Jiang Zhu, Zhongping Chen, K. Kelly, J. Nelson   +9 more
semanticscholar   +1 more source

Handheld, point-of-care laser speckle imaging

Journal of Biomedical Optics, 2016
. Laser speckle imaging (LSI) enables measurement of relative changes in blood flow in biological tissues. We postulate that a point-of-care form factor will lower barriers to routine clinical use of LSI. Here, we describe a first-generation handheld LSI
R. Farraro, Omid Fathi, Bernard Choi
semanticscholar   +1 more source

Enhanced dose prediction for head and neck cancer artificial intelligence‐driven radiotherapy based on transfer learning with limited training data

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Training deep learning dose prediction models for the latest cutting‐edge radiotherapy techniques, such as AI‐based nodal radiotherapy (AINRT) and Daily Adaptive AI‐based nodal radiotherapy (DA‐AINRT), is challenging due to limited data.
Hui‐Ju Wang, Austen Maniscalco, David Sher, Mu‐Han Lin, Steve Jiang, Dan Nguyen   +5 more
wiley   +1 more source