Results 181 to 190 of about 50,323 (284)

Multi‐Scale Mapping of Gene Expression from Whole‐slide Images for Identifying Phenotype‐Associated Subpopulations

Advanced Science, EarlyView.
BiSCALE: A pathology‐driven deep learning framework for multi‐scale gene expression prediction from whole‐slide images. It accurately infers bulk and near‐cellular spot‐level expression, links predictions to clinical phenotypes, identifies disease‐associated niches, and enables applications in risk stratification and cell‐identity annotation, providing
Hailong Zheng, Jiajing Xie, Luqi Wang, Hailong Xie, Tong Zhi, Yujia Guo, Bofeng Zhu, Dong Wang, Yu Chen   +8 more
wiley   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Spin‐Selective Interface Engineering in Oxide–Ferromagnetic Junctions via Atomic‐Scale Oxygen Control

Advanced Science, EarlyView.
We show that interfacial oxygen at the MgO/Fe interface can be transformed from an uncontrolled variable into a tunable design parameter for spintronic junctions. Momentum microscopy provides direct access to the momentum‐ and spin‐resolved electronic structure beneath the insulating MgO layers, revealing how oxygen intercalation reshapes buried Fe ...
David Maximilian Janas, Mira Sophie Arndt, Jonah Elias Nitschke, Lasse Sternemann, Valentin Mischke, Vitaliy Feyer, Iulia Cojocariu, Daniel Baranowski, Alessandro Sala, Andreas Windischbacher, Peter Puschnig, Jan Dreiser, Stefano Ponzoni, Giovanni Zamborlini, Mirko Cinchetti   +14 more
wiley   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

Advanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv, Qianyang Wu, Jian Liu, Binlu Yang, Yuanhao Li, Junlin Xu, Yajie Meng, Leyi Wei, Zilong Zhang, Quan Zou, Xiulai Li, Feifei Cui   +11 more
wiley   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Bioinspired Hierarchical Architecture with Water Transport Channels for Strong Adhesion at the Sweating Interface

Advanced Science, EarlyView.
To address adhesion failure in sweaty epidermal electronics, this study proposes a cross‐species, multi‐scale biomimetic interface. By modeling staged wet adhesion, it integrates self‐regulating liquid bridges with directional drainage. This design ensures stable, high‐performance flexible sensing in complex physiological environments, offering a ...
Jieliang Zhao, Yu Xiang, Heng Wang, Huiqing Xu, Zhong Liu, Lulu Liang, Fengwen Jiang, Xuemei Chen, Wenzhong Wang, Chenqing Liu, Guodong Liu, Shaoze Yan, Xu Hou   +12 more
wiley   +1 more source

Hierarchical Reconfigurable Metasurface Based on Scenario‐Guided Functional Modules and Programmable Core

Advanced Science, EarlyView.
This paper proposes a hierarchical reconfigurable metasurface architecture (HRMA) to achieve comprehensive electromagnetic parameter modulation and on‐demand polymorphic function switching. The reconfigurable metasurface is divided into a programmable core (PC) and scenario‐guided functional modules (FMs), exhibiting significant flexibility and ...
Lihao Zhu, Jiaqi Han, Zhe Zheng, Qiang Feng, Dexiao Xia, Xiangjin Ma, Yajie Mu, Guoliang Luo, Rui Li, Haixia Liu, Hao Xue, Long Li   +11 more
wiley   +1 more source

Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays

Advanced Science, EarlyView.
An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen, Bin Li, Yingying Wang, Fulin Zhu, Wenxuan Yang, Xuanyu Fu, Tiantian Man, Qiuyue Wu, Kewei Ren, Shengyuan Deng   +9 more
wiley   +1 more source