Results 51 to 60 of about 61,457 (342)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Methods for Determination of Mean Speckle Size in Simulated Speckle Pattern

open access: yesMeasurement Science Review, 2014
This paper deals with computation of mean speckle size in a speckle pattern generated through a numerical simulation of speckle after reflection of a Gaussian beam off a rough object’s surface. Within this simulation various speckle patterns are obtained
Hamarová I.   +3 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Surface Roughness Measurement Using Dichromatic Speckle Pattern: An Experimental Study [PDF]

open access: yes, 1978
Surface roughness is studied experimentally by making use of the statistical properties of dichromatic speckle patterns. The rms intensity difference between two speckle patterns produced by two argon laser lines are analyzed in the far field as ...
Fujii, Hitoshi, Lit, John W.Y.
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

A Novel Central Camera Calibration Method Recording Point-to-Point Distortion for Vision-Based Human Activity Recognition

open access: yesSensors, 2022
The camera is the main sensor of vison-based human activity recognition, and its high-precision calibration of distortion is an important prerequisite of the task. Current studies have shown that multi-parameter model methods achieve higher accuracy than
Ziyi Jin   +9 more
doaj   +1 more source

Non-contact optical in-vivo sensing of cilia motion by analyzing speckle patterns [PDF]

open access: gold, 2022
Doron Duadi   +3 more
openalex   +1 more source

Generating non-Rayleigh speckles with tailored intensity statistics

open access: yes, 2014
We experimentally generate speckle patterns with non-Rayleigh intensity statistics using a phase-only spatial light modulator. By introducing high order correlations to the input light fields we redistribute the intensity among the speckle grains, while ...
Bromberg, Yaron, Cao, Hui
core   +1 more source

Normalized ghost imaging [PDF]

open access: yes, 2012
We present an experimental comparison between different iterative ghost imaging algorithms. Our experimental setup utilizes a spatial light modulator for generating known random light fields to illuminate a partially-transmissive object.
Baoqing Sun   +15 more
core   +3 more sources

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