Results 71 to 80 of about 61,457 (342)

Exploiting speckle correlations to improve the resolution of wide-field fluorescence microscopy [PDF]

open access: yes, 2014
Fluorescence microscopy is indispensable in nanoscience and biological sciences. The versatility of labeling target structures with fluorescent dyes permits to visualize structure and function at a subcellular resolution with a wide field of view. Due to
Bertolotti, Jacopo   +5 more
core   +4 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

A model for simulating speckle-pattern evolution based on close to reality procedures used in spectral-domain OCT

open access: yes, 2014
A robust model for simulating speckle pattern evolution in optical coherence tomography (OCT) depending on the OCT system parameters and tissue deformation is reported.
Gelikonov, G. V.   +4 more
core   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

A fiber optic intrusion monitoring system

open access: yesMoldavian Journal of the Physical Sciences, 2013
A fiber optic intrusion monitoring system comprises a multimode optical fiber, a coherent light source, a CCD, and a processor for generation of the output signal. The system is based on the principle of variation of speckle pattern in the far-field of a
Culeac, Ion   +5 more
doaj  

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

An Effective Computational Ghost Imaging Based on Noise Estimation and Elimination

open access: yesIEEE Access, 2020
To improve the quality of ghost image, we propose an efficient computational ghost imaging method in this article. The primary idea is to estimate the noise value of the ghost image by analyzing and eliminating the source of the noise. The innovativeness
Xiaoxia Wang, Jiangtao Xi, Fengbao Yang
doaj   +1 more source

Twisted speckle entities inside wavefront reversal mirrors

open access: yes, 2009
The previously unknown property of the optical speckle pattern reported. The interference of a speckle with an oppositely moving phase-conjugated speckle wave produces a randomly distributed ensemble of a twisted entities (ropes) surrounding optical ...
A. Yu Okulov   +6 more
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

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