Results 121 to 130 of about 18,237 (226)

Fetal Speckle Tracking Technology for Critical Aortic Stenosis: Advancing Through Innovation. [PDF]

Diagnostics (Basel)
Murlewska J, Witkowski S, Strzelecka I, Respondek-Liberska M.   +3 more
europepmc   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

Two-dimensional speckle-tracking echocardiography for evaluating left atrial remodeling in renal transplant recipients. [PDF]

Quant Imaging Med Surg
Li Y, Gan S, Zhou Y, Deng W, Pan S, Liang S, Ou A, Xu L.   +7 more
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Correction: Integrative speckle-tracking echocardiography for the early detection and prediction of cancer therapy-related cardiac dysfunction. [PDF]

Cardiooncology
Qiu S, Zhang Y, Hou Y, Chen S, Yu H, Li H, Zhao L, Zhang X, Zhang X, Liu J, Yuan L, Duan Y, Xing C.   +12 more
europepmc   +1 more source

Speckle tracking echocardiography in cardiac sarcoidosis

International Journal of Cardiology, 2014
Uyarel, Huseyin, Guvenc, Tolga Sinan, Kul, Seref   +2 more
openaire   +3 more sources

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

Clinical Applications of Speckle-Tracking Echocardiography in Heart Failure: From Diagnosis to Prognostication. [PDF]

Int J Heart Fail
Lee JH, Park JH.
europepmc   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Early Detection of Diabetic Cardiomyopathy Using Speckle Tracking Echocardiography: A Systematic Review. [PDF]

Cureus
Burhanuddin M, Ahmed Z, Hamza A, Zeeshan M, Abdul Rehman F, Gillani SHM, Gul A, Rabbani Z, Omonfuegbe OM, Ali SM.   +9 more
europepmc   +1 more source