Results 171 to 180 of about 95,958 (315)

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

open access: yesMedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes   +4 more
wiley   +1 more source

The Safety and Efficacy of Targeted Alpha Therapy, Ac‐225 Prostate‐Specific Membrane Antigen, in Patients With Metastatic Castration‐Resistant Prostate Cancer: A Systematic Review and Meta‐Analysis

open access: yesThe Prostate, Volume 85, Issue 6, Page 541-557, May 2025.
ABSTRACT Background Metastatic castration resistance prostate cancer (mCRPC) is a challenging disease with a significant burden of mortality and morbidity. Most of the patients attain resistance to the available treatments, necessitating further novel therapies in this clinical setting.
Huseyin Besiroglu, Mustafa Kadihasanoglu
wiley   +1 more source

460. Evalution of Functional Image by ^<123>I-IMP Brain SPECT

open access: bronze, 1990
HIROSI GAKUMAZAWA   +3 more
openalex   +2 more sources

Volumetric Changes in Cerebellar Transverse Zones: Age and Sex Effects in Health and Neurological Disorders

open access: yesHuman Brain Mapping, Volume 46, Issue 6, April 15, 2025.
This study charts age‐ and sex‐dependent cerebellar volumetric changes, revealing transverse zone‐specific patterns and introducing a novel framework for estimating cerebellum age. These findings highlight cerebellar vulnerability in aging and disorders, offering insights into neurodegeneration and potential biomarkers for early detection.
Farshid Ghiyamihoor   +21 more
wiley   +1 more source

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