Results 121 to 130 of about 228,575 (301)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

«Klaatu barada nikto», una filosofía del espectador: Juan J. Alonso, Bibliotecaria, solterona y con gafas: diálogos, personajes y escenas que chirrían en 41 películas maravillosas. Gijón, Rema y Vive, 2025, 341 pp.

Eikasía
Even in films as perfect as Blade Runner (Ridley Scott, 1982) or Rear Window (Hitchcock, 1954), there are those strange moments that «take» you out of the film.
Pablo Huerga Melcón
doaj  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

“Ne restez pas simple spectateur”. Lo spettatore contemporaneo tra online e offline. Il caso allocine.fr

Cinergie, 2012
Giacomo Di Foggia
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Turkish Adaptation of Stadium Atmosphere Scale: A Comparison of Football Spectators and Fans

Pamukkale Spor Bilimleri Dergisi
This study aimed to test the Turkish adaptation of the Stadium Atmosphere Scale (STAS) and reveal its psychometric properties. We collected data from 324 football spectators and fans, which were selected using the convenience sampling method.
Buğra Akay, Fatih Yaşartürk, İsmail Aydın   +2 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

En Inde, dans les salles de cinéma, les spectateurs sont-ils acteurs ou simples spectateurs ?

Conserveries Mémorielles, 2012
The spectator’s role in general is often questioned, but in the case of Indian spectators, it takes a whole new turn. Indeed, in India, since the arrival of cinema, members of the audience do not content themselves with being simply spectators of the ...
Wendy Cutler
doaj