Results 211 to 220 of about 228,575 (301)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Movement beyond data: epistemic and pictorial challenges in understanding moving life. [PDF]

Front Bioinform
Wellmann J.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Role of Spectator Species for Amine-Surface Chemistry: Reactions of Amines and Alkenes on Pt(111). [PDF]

J Am Chem Soc
Brinkmann N, Austin D, Ashraf B, Le D, Rahman TS, Al-Shamery K.   +5 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Timing the escape of a photoexcited electron from a molecular cage. [PDF]

Nat Commun
Fields C, Foerster A, Ghaderzadeh S, Popov I, Huynh B, Junqueira F, James T, Alonso Perez S, Duncan DA, Lee TL, Wang Y, Bloodworth S, Hoffman G, Walkey M, Whitby RJ, Levitt MH, Kiraly B, O'Shea JN, Besley E, Moriarty P.   +19 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Charge transfer dynamics in noble gas endofullerenes: intra- and extramolecular tunnelling. [PDF]

Nanoscale Adv
Sufyan A, James T, Fields C, Naseri S, Junqueira F, Alonso-Perez S, Bloodworth S, Hoffman G, Walkey MC, Marsden ES, Whitby RJ, Wang Y, Duncan DA, Lee TL, O'Shea JN, Larsson JA, Kiraly B, Moriarty P.   +17 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Site- and Energy-Selective Low-Energy Electron Emission by X-rays in the Aqueous Phase. [PDF]

J Am Chem Soc
Bloß D, Dupuy R, Trinter F, Unger I, Walsh N, Öhrwall G, Golchert N, Klassen G, Krone A, Terao Y, Viehmann JH, Wülfing L, Richter C, Buttersack T, Cederbaum LS, Hergenhahn U, Björneholm O, Ehresmann A, Hans A.   +18 more
europepmc   +1 more source