Results 31 to 40 of about 2,681,308 (310)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Molecular Vibrations in Chiral Europium Complexes Revealed by Near‐Infrared Raman Optical Activity

open access: yesAdvanced Science
Raman optical activity (ROA) is commonly measured with green light (532 nm) excitation. At this wavelength, however, Raman scattering of europium complexes is masked by circularly polarized luminescence (CPL).
Tao Wu   +3 more
doaj   +1 more source

Extreme Waves in the Agulhas Current Region Inferred from SAR Wave Spectra and the SWAN Model

open access: yesJournal of Marine Science and Engineering, 2021
The influence of the Agulhas Current on the wave field is investigated. The study is conducted by performing high resolution spectral wave model simulations with and without ocean currents. The validation of the numerical simulations is performed for the
Sonia Ponce de León, C. Guedes Soares
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Reflectance spectra obtained from FDTD simulations.

open access: yes, 2023
A Four simulated sections of the barbule, each with a height of around 1 μm, corresponding to the size of the color domain. Enlarged images are presented in S3 Fig. B Spectra for the sections of the barbule calculated from the FDTD simulations.
Heeso Noh (196506)   +4 more
core   +1 more source

Dynamic spectra of type III radio emissions from particle-in-cell simulations

open access: yesAstronomy & Astrophysics
Realistic modeling of type III solar radio bursts is essential for remotely diagnosing their exciters, the driving electron beams, and the ambient plasma.
Lazar M.   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Monte Carlo Simulations of ED-XRF Spectra as an Authentication Tool for Nuragic Bronzes

open access: yesHeritage, 2021
The high artistic and cultural relevance of particular objects, in this case from the Nuragic civilization, have stimulated the growth of a forgery industry, replicating small bronze boats (navicelle), statues (bronzetti), and other objects.
Carlo Nocco   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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