Results 101 to 110 of about 702,163 (313)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Study on defect type in eddy-current testing based on phase spectrum analysis
The Journal of Engineering, 2019 This article proposes the use of phase angle gradient as a feature to detect and classify different types of defects. Based on the principle of eddy-current testing (ECT), the ECT platform was designed and manufactured.
Ronghua Zhang, Song Ye
doaj +1 more source
, 2019 The content of silicon and iron in primary aluminum were detected by self-built LIBS device. The micro-morphology analysis of the primary aluminum sample was carried out before the experiment, It was found the distribution of silicon element is ...
Ma Liang +5 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Cardiovascular Autonomic Profile in Women With Premenstrual Syndrome
Frontiers in Physiology, 2018 Introduction: The premenstrual syndrome (PMS) is a constellation of somatic and psychogenic symptoms that appear during late luteal (LL) phase of the menstrual cycle.
Rimma Koifman +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Suppression Method of Raman Laser Thermal Effect for Sensitive Samples
Laser-micro confocal Raman spectroscopy is widely used to study molecular structure, bonding effects. loading, and bternal stress. The signal intensity and quality of Raman spectra are particularly important for the analysis. However.
Su, Qiu-cheng +5 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Stability of an additive-quadratic functional equation in modular spaces
Open MathematicsUsing the direct method, we prove the Hyers-Ulam-Rassias stability of the following functional equation: ϕ(x+y,z+w)+ϕ(x−y,z−w)−2ϕ(x,z)−2ϕ(x,w)=0\phi \left(x+y,z+w)+\phi \left(x-y,z-w)-2\phi \left(x,z)-2\phi \left(x,w)=0 in ρ\rho -complete convex modular ...
Baza Abderrahman +3 more
doaj +1 more source
, 2018 Liquid oxidation techniques by sub-molten salt media for the effective extraction of amphoteric metal from refractory minerals have been developed. An innovative synergistic process by electrochemical oxidation and reactive oxygen species (ROS) intensify
Zhang Yi +3 more
core +1 more source