Results 131 to 140 of about 24,551,019 (389)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Robust Spectrum-Based Comparison of Multivariate Complex Random Signals

open access: yesIEEE Access, 2019
We consider the problem of comparing two complex multivariate random signal realizations, possibly contaminated with additive outliers, to ascertain whether they have identical power spectral densities.
Jitendra K. Tugnait
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Spectral Efficiency Increase for Passive Backscatter Communication Based on Discrete Pulse Shaping

open access: yesIEEE Access, 2018
The Internet of Things comprises the network of billions of devices. The need for wireless systems is leading to bandwidth becoming an extremely limited resource.
Manuel Ferdik   +3 more
doaj   +1 more source

Making Laplacians commute [PDF]

open access: yes, 2013
In this paper, we construct multimodal spectral geometry by finding a pair of closest commuting operators (CCO) to a given pair of Laplacians. The CCOs are jointly diagonalizable and hence have the same eigenbasis.
Bronstein, Michael M.   +2 more
core  

Semiclassical and spectral analysis of oceanic waves

open access: yes, 2011
In this work we prove that the shallow water flow, subject to strong wind forcing and linearized around an adequate stationary profile, develops for large times closed trajectories due to the propagation of Rossby waves, while Poincar\'e waves are shown ...
Cheverry, Christophe   +3 more
core   +2 more sources

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