Results 131 to 140 of about 702,163 (313)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Investigation of N Deficiency in Cherry Trees Using Visible and Near-Infrared Spectra Part of the Spectrum in Field Condition

open access: yes, 2017
This objective of the study was to develop a model for the determination of N deficiency in cherry trees using a combination of visible near infrared methods and spectro-radiometric measurement.
Dedeoğlu, Mert   +4 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Modern spectral analysis in HF radar remote sensing. [PDF]

open access: yes, 1998
High-Frequency (HF) radar systems are currently used to collect wave data. By applying spectral analysis methods, such as the Fast Fourier Transform (FFT) method, to the radar backscatter from the ocean surface, the so-called Doppler spectrum is ...
Vizinho, A., Vizinho, A
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Coded Aperture Spectral Data Restoration Based on Two-Step Iterative Shrinkage/Threshold

open access: yes, 2014
Coded aperture imaging spectrometer based on the concept of compressed sensing can acquire the spectral diagram of object. Coded aperture spectral data restoration reconstructs three-dimensional data cube from two-dimensional coded image.
Wang Shuang   +4 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Ultrasonic characterisation of malignant melanoma of choroid

open access: yesIndian Journal of Ophthalmology, 1998
An in-vitro study of wave spectral analysis in 8 enucleated eyes was conducted in order to differentiate histological subtypes of malignant melanoma. To obtain the backscattering coefficient for the tissues, we used a broadband focussed transducer with a
John Sheila   +5 more
doaj  

A Solid Phase Extraction Application of Hybrid Nano B2O3/ZrO2 for Separation and Determination of Trace Indium in Environmental Samples

open access: yes, 2018
WOS: 000430996100049Hybrid nanomaterials have attracted considerable interest in environmental science, analytical chemistry and atomic spectroscopy. In the present study, a column solid phase extractioo procedure was developed for the separation and ...
Turker, Ali Rehber   +4 more
core   +1 more source

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