Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Face reverse degree topological analysis of TP-COFs, existence of isentropic COFs and spectral characteristics. [PDF]
Rajendran T +4 more
europepmc +1 more source
Spectral characteristics of gold nanoparticle doped optical fibre under axial strain. [PDF]
Wang X, Benedictus R, Groves RM.
europepmc +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Effects of ground motion spectral characteristics on RC frame fragility considering liquefaction. [PDF]
Fei Y, Chen LW, Gan SC, Tang LZ, Cui Z.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Spectral Characteristics of Dissolved Organic Matter and Their Associations with Heavy Metal Distribution in Multi-Media of a Typical Frozen Eutrophic Lake. [PDF]
Lv Z +8 more
europepmc +1 more source
Influence of the antiseptic octenidine on spectral characteristics and energy migration processes in photosystem II core complexes. [PDF]
Paschenko VZ +4 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Molecular Structural Features and Tandem Mass Spectral Characteristics of Flavonoids From the Analysis of the LIPID MAPS Database. [PDF]
Perumal U, Sabareesh V.
europepmc +1 more source

