Results 141 to 150 of about 1,152,425 (303)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Influence of Binaural Beats Stimulation of Gamma Frequency over Memory Performance and EEG Spectral Density. [PDF]

Healthcare (Basel), 2023
Borges LR, Arantes APBB, Naves ELM.
europepmc   +1 more source

Online Spectral Density Estimation

This paper develops the first online algorithms for estimating the spectral density function -- a fundamental object of interest in time series analysis -- that satisfies the three core requirements of streaming inference: fixed memory, fixed computational complexity, and temporal adaptivity.
Kazi, Shahriar Hasnat, Adams, Niall, Cohen, Edward A. K.   +2 more
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Assessment of power spectral density of microvascular hemodynamics in skeletal muscles at very low and low-frequency via near-infrared diffuse optical spectroscopies. [PDF]

Biomed Opt Express, 2023
Amendola C, Buttafava M, Carteano T, Contini L, Cortese L, Durduran T, Frabasile L, Guadagno CN, Karadeinz U, Lacerenza M, Mesquida J, Parsa S, Re R, Sanoja Garcia D, Konugolu Venkata Sekar S, Spinelli L, Torricelli A, Tosi A, Weigel UM, Yaqub MA, Zanoletti M, Contini D.   +21 more
europepmc   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Far-Zone Spectral Density of Light Waves Scattered by Random Anisotropic Hollow Medium

Photonics
A random anisotropic hollow scatterer is discussed and the far-zone characteristics of scalar light waves scattered by this type of medium are theoretically analyzed.
Yue Yu, Yongtao Zhang, Jixiong Pu, Huanting Chen, Huichuan Lin   +4 more
doaj   +1 more source

Power Spectral Density Analysis for Optimizing SERS Structures. [PDF]

Sensors (Basel), 2022
Babich E, Scherbak S, Lubyankina E, Zhurikhina V, Lipovskii A.   +4 more
europepmc   +1 more source