Results 51 to 60 of about 1,144,435 (297)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Spectral properties of the generalized diluted Wishart ensemble

Journal of Physics: Complexity, 2022
The celebrated Marčenko–Pastur law, that considers the asymptotic spectral density of random covariance matrices, has found a great number of applications in physics, biology, economics, engineering, among others.
Isaac Pérez Castillo
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Density-matrix renormalisation group approach to quantum impurity problems

, 2003
A dynamic density-matrix renormalisation group approach to the spectral properties of quantum impurity problems is presented. The method is demonstrated on the spectral density of the flat-band symmetric single-impurity Anderson model.
Berkovits R, Brandt U, Brandt U, Bulla R, Costi T A, E Jeckelmann, Frota H O, Gebhard F, Gebhard F Jeckelmann E Kalinowski E Nishimoto S, Gebhard F Jeckelmann E Mahlert S Nishimoto S Noack R M, Georges A, Glossop M T, Gubernatis J E, Hallberg K, Hallberg K A, Hettler M H, Hewson A C, Kühner T D, Leggett A J, Logan D E, Peschel I, Press W H, Raas C Uhrig G S Anders F B, Rosch A, S Nishimoto, Sorensen E S, Wang W, Wang X, White S R, Wilson K G, Zhang C   +30 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

InGaAs Diodes for Terahertz Sensing—Effect of Molecular Beam Epitaxy Growth Conditions

Sensors, 2018
InGaAs-based bow-tie diodes for the terahertz (THz) range are found to be well suited for development of compact THz imaging systems. To further optimize design for sensitive and broadband THz detection, one of the major challenges remains: to understand
Vilius Palenskis, Linas Minkevičius, Jonas Matukas, Domas Jokubauskis, Sandra Pralgauskaitė, Dalius Seliuta, Bronislovas Čechavičius, Renata Butkutė, Gintaras Valušis   +8 more
doaj   +1 more source

Research of the total spectral density of signals in the LTE up-link

Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki, 2020
This article is devoted to the analysis of the total spectral radiation density of LTE subscriber terminals. The LTE network uses orthogonal frequency division multiple access (OFDMA) technology for downlink communications, and multiple access technology
A. A. Novikova, V. M. Kozel, K. A. Kavaliou   +2 more
doaj   +1 more source

Dynamical decoupling noise spectroscopy

, 2011
Decoherence is one of the most important obstacles that must be overcome in quantum information processing. It depends on the qubit-environment coupling strength, but also on the spectral composition of the noise generated by the environment.
Alvarez, Gonzalo A., Suter, Dieter
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source