Results 111 to 120 of about 6,450,359 (383)

Spectral phase conjugation with cross-phase modulation compensation [PDF]

, 2004
Spectral phase conjugation with short pump pulses in a third-order nonlinear material is analyzed in depth. It is shown that if signal amplification is considered, the conversion efficiency can be significantly higher than previously considered, while ...
Psaltis, Demetri, Tsang, Mankei
core  

Caching Policy Toward Maximal Success Probability and Area Spectral Efficiency of Cache-Enabled HetNets [PDF]

IEEE Transactions on Communications, 2016
In this paper, we investigate the optimal caching policy, respectively, maximizing the success probability and area spectral efficiency (ASE) in a cache-enabled heterogeneous network (HetNet), where a tier of multi-antenna macro base stations (MBSs) is ...
Dong Liu, Chenyang Yang
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Laser Phase Noise Tolerant and Power-Fading-Free Hybrid Fiber-Wireless Double-Sideband Transmission With Spectral Efficiency Enhancement

IEEE Photonics Journal
The photonics-assisted millimeter-wave (MMW) communication technology is attractive to facilitate the MMW application in the upcoming B5G and 6G networks.
Jiankang Li, Yuancheng Cai, Shitong Xiang, Xiaoguang Yang, Mingzheng Lei, Bingchang Hua, Jiao Zhang, Junjie Ding, Yucong Zou, Xingyu Chen, Xiang Liu, Yunwu Wang, Jianjun Yu, Min Zhu   +13 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Wireless Energy Harvesting with Cooperative Relaying under the Best Relay Selection Scheme

Energies, 2019
One of the most notable challenges in wireless communications is energy scarcity, which has attracted considerable attention in Fifth Generation (5G) wireless network research.
Admoon Andrawes, Rosdiadee Nordin, Mahamod Ismail   +2 more
doaj   +1 more source

Time-Frequency Packing for High Capacity Coherent Optical Links

, 2014
We consider realistic long-haul optical links, with linear and nonlinear impairments, and investigate the application of time-frequency packing with low-order constellations as a possible solution to increase the spectral efficiency.
Colavolpe, Giulio, Foggi, Tommaso
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source