Results 171 to 180 of about 92,516 (310)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Spectroscopy-informed XANES-PXRD framework for multi-property prediction and structure inference. [PDF]

Chem Sci
Wang Y, Zhao S, Luo M, Zeng H, Feng Y, Liu D, Huang Y, Jiang J.   +7 more
europepmc   +1 more source

A quantitative assessment of random field models in finite element buckling analyses of composite cylinders

, 2012
Large scatter characterizes the collapse load of thin-walled structures due to their imperfection sensitivity. Random fields can be used to include imperfections in a finite element model.
Degenhardt, Richard, De Groof, L., Haller, H., Oberguggenberger, M., Kling, Alexander   +4 more
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Adaptive Resonance Demodulation for Bearing Fault Diagnosis via Spectral Trend Reconstruction and Weighted Logarithmic Energy Ratio. [PDF]

Sensors (Basel)
Feng Q, Chen Y, Dai Q, Wang J, Hu J, Wu L, Qin R.   +6 more
europepmc   +1 more source

Unsteady Navier-Stokes Solvers Using Hybrid

, 2007
A domain decomposition unsteady Stokes solver has been implemented in a hybrid spectral/hp element solver. To extend the algorithm to solve the Navier-Stokes equations the non-linear terms are explicitly advanced in time and treated as a forcing ...
Spectral Hp Element, Spencer J. Sherwin, Mark Ainsworth   +2 more
core  

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Pipeline Flange Bolt Loosening Detection Technology Based on Stress Waves and Deep Learning. [PDF]

Sensors (Basel)
Yu C, Cheng P, Shao C, Guo Y, Cheng L, Sun C.   +5 more
europepmc   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

A Rolling Bearing Fault Diagnosis Method Based on PSO-Optimized FHN Stochastic Resonance. [PDF]

Sensors (Basel)
Wang Z, Chen Y, Dai Q, Wang J, Hu J, Wu L, Qin R.   +6 more
europepmc   +1 more source