Results 91 to 100 of about 7,136,334 (313)
Spectral flow inside essential spectrum [PDF]
, 2014 The spectral flow is a classical notion of functional analysis and differential geometry which was given different interpretations as Fredholm index, Witten index, and Maslov index. The classical theory treats spectral flow outside the essential spectrum.
N. Azamov
semanticscholar +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Spectral flow as a map between N=(2,0)-models [PDF]
, 2014 The space of ( 2 , 0 ) models is of particular interest among all heterotic-string models because it includes the models with the minimal SO ( 10 ) unification structure, which is well motivated by the Standard Model of particle physics data.
P. Athanasopoulos, A. Faraggi, D. Gepner
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
BASIC FUNCTIONAL ANALYSIS PUZZLES OF SPECTRAL FLOW [PDF]
Journal of the Australian Mathematical Society, 2011 AbstractWe explain an array of basic functional analysis puzzles on the way to general spectral flow formulae and indicate a direction of future topological research for dealing with these puzzles.
openaire +2 more sources
, 2015 Transient black hole candidates are interesting objects to study in X-rays as these sources show rapid evolutions in their spectral and temporal properties. In this paper, we study the spectral properties of the Galactic transient X-ray binary MAXI~J1659-
Chakrabarti, Sandip K. +3 more
core +1 more source
A Graph Spectral Flow for Computing Nodal Deficiencies [PDF]
, 2020 Wesley Hamilton
openalex +1 more source
General Spectral Flow Formula for Fixed Maximal Domain
, 2005 We consider a continuous curve of linear elliptic formally self-adjoint differential operators of first order with smooth coefficients over a compact Riemannian manifold with boundary together with a continuous curve of global elliptic boundary value ...
A. Floer +30 more
core +2 more sources