Results 121 to 130 of about 6,503,496 (355)

The Joint Spectral Flow and Localization of the Indices of Elliptic Operators [PDF]

, 2014
We introduce the notion of the joint spectral flow, which is a generalization of the spectral flow, by using Segal's model of the connective $K$-theory spectrum.
Yosuke Kubota
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Novel full‐spectral flow cytometry with multiple spectrally‐adjacent fluorescent proteins and fluorochromes and visualization of in vivo cellular movement

Cytometry Part A, 2015
Flow cytometric analysis with multicolor fluoroprobes is an essential method for detecting biological signatures of cells. Here, we present a new full‐spectral flow cytometer (spectral‐FCM).
Koji Futamura, M. Sekino, Akihiro Hata, R. Ikebuchi, Yasutaka Nakanishi, G. Egawa, K. Kabashima, Takeshi Watanabe, M. Furuki, M. Tomura   +9 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Accretion Flow Dynamics of MAXI J1659-152 from the Spectral Evolution Study of its 2010 Outburst using the TCAF Solution

, 2015
Transient black hole candidates are interesting objects to study in X-rays as these sources show rapid evolutions in their spectral and temporal properties. In this paper, we study the spectral properties of the Galactic transient X-ray binary MAXI~J1659-
Chakrabarti, Sandip K., Debnath, Dipak, Molla, Aslam Ali, Mondal, Santanu   +3 more
core   +1 more source

A review of medical doppler ultrasonography of blood flow in general and especially in common carotid artery

Journal of Medical Ultrasound, 2018
Medical Doppler ultrasound is usually utilized in the clinical adjusting to evaluate and estimate blood flow in both the major (large) and the minor (tiny) vessels of the body.
Ammar A Oglat, M Z Matjafri, Nursakinah Suardi, Mohammad A Oqlat, Mostafa A Abdelrahman, Ahmad A Oqlat   +5 more
doaj   +1 more source

Fully implicit spectral boundary integral computation of red blood cell flow [PDF]

, 2021
Pei-Chuan Chao, Ali Gürbüz, Frederick Sachs, M. V. Sivaselvan   +3 more
openalex   +1 more source

BASIC FUNCTIONAL ANALYSIS PUZZLES OF SPECTRAL FLOW [PDF]

Journal of the Australian Mathematical Society, 2011
AbstractWe explain an array of basic functional analysis puzzles on the way to general spectral flow formulae and indicate a direction of future topological research for dealing with these puzzles.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source