Results 131 to 140 of about 5,178,293 (354)

Satellite-Derived Spectral Index Analysis for Drought and Groundwater Monitoring in Doñana Wetlands: A Tool for Informed Conservation Strategies

open access: yesGeographies
Climate change and increased human activity are causing the Doñana wetlands, an important ecological reserve in southern Europe, to lose water more quickly.
Emilio Ramírez-Juidias   +2 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

On the Semi-Automatic Retrieval of Biophysical Parameters Based on Spectral Index Optimization

open access: yesRemote Sensing, 2014
Regression models based on spectral indices are typically empirical formulae enabling the mapping of biophysical parameters derived from Earth Observation (EO) data. Due to its empirical nature, it remains nevertheless uncertain to what extent a selected
J. P. Rivera   +4 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Adjusting Spectral Indices for Spectral Response Function Differences of Very High Spatial Resolution Sensors Simulated from Field Spectra

open access: yesSensors, 2015
The use of data from multiple sensors is often required to ensure data coverage and continuity, but differences in the spectral characteristics of sensors result in spectral index values being different. This study investigates spectral response function
Sharon L. Cundill   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The Spectral Shift Function and the Witten Index [PDF]

open access: yes, 2016
We survey the notion of the spectral shift function of a pair of self-adjoint operators and recent progress on its connection with the Witten index. We also describe a proof of Krein's Trace Theorem that does not use complex analysis [53] and develop its extension to general $ $-finite von Neumann algebras $\mathcal{M}$ of type II and unbounded ...
Carey, Alan L   +3 more
openaire   +3 more sources

The APS-index and the spectral flow [PDF]

open access: diamond, 2021
Koen van den Dungen, Lennart Ronge
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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