Results 131 to 140 of about 5,178,293 (354)
Climate change and increased human activity are causing the Doñana wetlands, an important ecological reserve in southern Europe, to lose water more quickly.
Emilio Ramírez-Juidias +2 more
doaj +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
On the Semi-Automatic Retrieval of Biophysical Parameters Based on Spectral Index Optimization
Regression models based on spectral indices are typically empirical formulae enabling the mapping of biophysical parameters derived from Earth Observation (EO) data. Due to its empirical nature, it remains nevertheless uncertain to what extent a selected
J. P. Rivera +4 more
semanticscholar +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The use of data from multiple sensors is often required to ensure data coverage and continuity, but differences in the spectral characteristics of sensors result in spectral index values being different. This study investigates spectral response function
Sharon L. Cundill +2 more
doaj +1 more source
Spectral extremal results on the $α$-index of graphs without minors and star forests [PDF]
Mingzhu Chen +2 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Spectral Shift Function and the Witten Index [PDF]
We survey the notion of the spectral shift function of a pair of self-adjoint operators and recent progress on its connection with the Witten index. We also describe a proof of Krein's Trace Theorem that does not use complex analysis [53] and develop its extension to general $ $-finite von Neumann algebras $\mathcal{M}$ of type II and unbounded ...
Carey, Alan L +3 more
openaire +3 more sources
The APS-index and the spectral flow [PDF]
Koen van den Dungen, Lennart Ronge
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

