Results 151 to 160 of about 5,178,293 (354)

The Conley index and spectral sequences

open access: yesTopological Methods in Nonlinear Analysis, 2005
The author proves the existence and uniqueness of spectral sequences for the filtration associated to the totally ordered Morse decomposition of an isolated invariant set.
openaire   +3 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spectral triples: examples and index theory

open access: yes, 2011
The main objective of these notes is to give some intuition about spectral triples and the role they play in index theory. The notes are basically a road map, with much detail omitted. To give a complete account of all the topics covered would require at least a book, so we have opted for a sketch.
Carey, Alan L   +2 more
openaire   +2 more sources

Enhancing the Performance of Unmanned Aerial Vehicle-Based Estimation of Rape Chlorophyll Content by Reducing the Impact of Crop Coverage

open access: yesDrones
Estimating leaf chlorophyll content (LCC) in a timely manner and accurately is of great significance for the precision management of rape. The spectral index derived from UAV images has been adopted as a non-destructive and efficient way to map LCC ...
Yaxiao Niu   +7 more
doaj   +1 more source

Visualization And Indexing Of Spectral Databases

open access: yes, 2012
{"references": ["H. Yamamotoa, H. Yamaji, E. Fukusaki, H. Fukuda, Canonical correlation\nanalysis for multivariate regression and its application to metabolic\nfingerprinting, Biochemical Engineerin Journal 40 (2008) 199-204.", "J. Parkkinen, A.C.
Kulcsar, Tibor   +4 more
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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